IL-15 AND IL-15RALPHA SUSHI DOMAIN BASED CONJUGATES

The present invention relates to an immunocytokine comprising (a) a conjugate, and (b) an antibody or a fragment thereof directly or indirectly linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or deriva...

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Hauptverfasser: ROBERT, Bruno Gilbert Marc, BECHARD, David, JACQUES, Yannick Laurent Joseph, DE MARTYNOFF, Guy Luc Michel, TEPPAZ, Géraldine, MORISSEAU, Sébastien Daniel
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creator ROBERT, Bruno Gilbert Marc
BECHARD, David
JACQUES, Yannick Laurent Joseph
DE MARTYNOFF, Guy Luc Michel
TEPPAZ, Géraldine
MORISSEAU, Sébastien Daniel
description The present invention relates to an immunocytokine comprising (a) a conjugate, and (b) an antibody or a fragment thereof directly or indirectly linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and a polypeptide comprising the amino acid sequence of the sushi domain of the IL-15R± or derivatives thereof; and uses thereof.
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language eng ; fre ; ger
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title IL-15 AND IL-15RALPHA SUSHI DOMAIN BASED CONJUGATES
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