IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY

The present invention relates generally to the use of LSD1 inhibitors in connection with use and manufacture of immune effector cells (e.g., T cells, NK cells), e.g., engineered to express a chimeric antigen receptor (CAR), to treat a subject having a disease, e.g., a disease associated with express...

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Hauptverfasser: XIAO, Qitao, MAVRAKIAS, Konstantinos John, LIU, Lei, ZHENG, Qiangang, MOTZ, Gregory, LIU, Jinbiao, XUN, Guoliang
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Sprache:eng ; fre ; ger
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creator XIAO, Qitao
MAVRAKIAS, Konstantinos John
LIU, Lei
ZHENG, Qiangang
MOTZ, Gregory
LIU, Jinbiao
XUN, Guoliang
description The present invention relates generally to the use of LSD1 inhibitors in connection with use and manufacture of immune effector cells (e.g., T cells, NK cells), e.g., engineered to express a chimeric antigen receptor (CAR), to treat a subject having a disease, e.g., a disease associated with expression of a tumor antigen.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title IMMUNE EFFECTOR CELL THERAPIES WITH ENHANCED EFFICACY
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