CRYSTAL FORM OF OREXIN RECEPTOR ANTAGONIST COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREOF

Disclosed are a preparation method of an orexin receptor antagonist compound 5-3, crystalline forms I-IV of the compound and preparation method thereof, and application of the crystalline forms in preparation of a drug treating a disease associated with orexin.

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Hauptverfasser: QIN, Dakun, CHEN, Yuan, WANG, Yuhe, WU, Songliang, LI, Weidong, LI, Xiaolin, WANG, Zheng, LUO, Zhi, HE, Haiying
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creator QIN, Dakun
CHEN, Yuan
WANG, Yuhe
WU, Songliang
LI, Weidong
LI, Xiaolin
WANG, Zheng
LUO, Zhi
HE, Haiying
description Disclosed are a preparation method of an orexin receptor antagonist compound 5-3, crystalline forms I-IV of the compound and preparation method thereof, and application of the crystalline forms in preparation of a drug treating a disease associated with orexin.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title CRYSTAL FORM OF OREXIN RECEPTOR ANTAGONIST COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREOF
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