3-((4-ISOQUINOLIN-3-YL)METHYL)-1H-IMIDAZO[4,5-C]PYRIDIN-2(3H)-ONE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF REPLICATION OF THE RESPIRATORY SYNCYTIAL VIRUS (RSV)
Compounds of Formula (I): (Formula I), wherein Z1 is NR1A, CHR1A or CR1BR1B; one of Z2 and Z3 is CH or CR1A', the other is N, CH or CR1A'; n is 0, 1 or 2; q is 0, 1 or 2; R1A, R1A', R1B, R2 and R3 are as defined herein, their use as inhibitors of RSV and related aspects.
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| creator | KUHN, Cyrille AYESA, Susana LEIJONMARCK, Marie GHIRO, Elise BERTRAND, Megan STURINO, Claudio BROCHU, Christian WESTERLIND, Hans SEHGELMEBLE, Fernando BYLUND, Johan ERSMARK, Karolina KALAYANOV, Gennadiy WÄHLING, Horst SALVADOR ODEN, Lourdes |
| description | Compounds of Formula (I): (Formula I), wherein Z1 is NR1A, CHR1A or CR1BR1B; one of Z2 and Z3 is CH or CR1A', the other is N, CH or CR1A'; n is 0, 1 or 2; q is 0, 1 or 2; R1A, R1A', R1B, R2 and R3 are as defined herein, their use as inhibitors of RSV and related aspects. |
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BERTRAND, Megan ; STURINO, Claudio ; BROCHU, Christian ; WESTERLIND, Hans ; SEHGELMEBLE, Fernando ; BYLUND, Johan ; ERSMARK, Karolina ; KALAYANOV, Gennadiy ; WÄHLING, Horst ; SALVADOR ODEN, Lourdes</creator><creatorcontrib>KUHN, Cyrille ; AYESA, Susana ; LEIJONMARCK, Marie ; GHIRO, Elise ; BERTRAND, Megan ; STURINO, Claudio ; BROCHU, Christian ; WESTERLIND, Hans ; SEHGELMEBLE, Fernando ; BYLUND, Johan ; ERSMARK, Karolina ; KALAYANOV, Gennadiy ; WÄHLING, Horst ; SALVADOR ODEN, Lourdes</creatorcontrib><description>Compounds of Formula (I): (Formula I), wherein Z1 is NR1A, CHR1A or CR1BR1B; one of Z2 and Z3 is CH or CR1A', the other is N, CH or CR1A'; n is 0, 1 or 2; q is 0, 1 or 2; R1A, R1A', R1B, R2 and R3 are as defined herein, their use as inhibitors of RSV and related aspects.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180606&DB=EPODOC&CC=EP&NR=3328859A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180606&DB=EPODOC&CC=EP&NR=3328859A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KUHN, Cyrille</creatorcontrib><creatorcontrib>AYESA, Susana</creatorcontrib><creatorcontrib>LEIJONMARCK, Marie</creatorcontrib><creatorcontrib>GHIRO, Elise</creatorcontrib><creatorcontrib>BERTRAND, Megan</creatorcontrib><creatorcontrib>STURINO, Claudio</creatorcontrib><creatorcontrib>BROCHU, Christian</creatorcontrib><creatorcontrib>WESTERLIND, Hans</creatorcontrib><creatorcontrib>SEHGELMEBLE, Fernando</creatorcontrib><creatorcontrib>BYLUND, Johan</creatorcontrib><creatorcontrib>ERSMARK, Karolina</creatorcontrib><creatorcontrib>KALAYANOV, Gennadiy</creatorcontrib><creatorcontrib>WÄHLING, Horst</creatorcontrib><creatorcontrib>SALVADOR ODEN, Lourdes</creatorcontrib><title>3-((4-ISOQUINOLIN-3-YL)METHYL)-1H-IMIDAZO[4,5-C]PYRIDIN-2(3H)-ONE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF REPLICATION OF THE RESPIRATORY SYNCYTIAL VIRUS (RSV)</title><description>Compounds of Formula (I): (Formula I), wherein Z1 is NR1A, CHR1A or CR1BR1B; one of Z2 and Z3 is CH or CR1A', the other is N, CH or CR1A'; n is 0, 1 or 2; q is 0, 1 or 2; R1A, R1A', R1B, R2 and R3 are as defined herein, their use as inhibitors of RSV and related aspects.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNi8FKAzEURWfjQrT_8JYzYBZtWqjLmLySB5m8NMkMRJFSJF0VLdSf8i8bwQ9wdbiHc--7Hyn6fi0o8X4iz468kKK4YcRsG8TSChrJqFd-Wz9thH4PJZJp1aqXdhDsEQxGmlWmGRMobyCiUxkNaB4DT940m4C8pRfKHBPwriXBkW4f9r8zW2wqBYqqFQVS8bpkUg5milOCPqZ5eOzuTsfztS7--NDBDrO2ol6-DvV6OX7Uz_p9wCDlarvdPKul_EdyA7IURms</recordid><startdate>20180606</startdate><enddate>20180606</enddate><creator>KUHN, Cyrille</creator><creator>AYESA, Susana</creator><creator>LEIJONMARCK, Marie</creator><creator>GHIRO, Elise</creator><creator>BERTRAND, Megan</creator><creator>STURINO, Claudio</creator><creator>BROCHU, Christian</creator><creator>WESTERLIND, Hans</creator><creator>SEHGELMEBLE, Fernando</creator><creator>BYLUND, Johan</creator><creator>ERSMARK, Karolina</creator><creator>KALAYANOV, Gennadiy</creator><creator>WÄHLING, Horst</creator><creator>SALVADOR ODEN, Lourdes</creator><scope>EVB</scope></search><sort><creationdate>20180606</creationdate><title>3-((4-ISOQUINOLIN-3-YL)METHYL)-1H-IMIDAZO[4,5-C]PYRIDIN-2(3H)-ONE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF REPLICATION OF THE RESPIRATORY SYNCYTIAL VIRUS (RSV)</title><author>KUHN, Cyrille ; AYESA, Susana ; LEIJONMARCK, Marie ; GHIRO, Elise ; BERTRAND, Megan ; STURINO, Claudio ; BROCHU, Christian ; WESTERLIND, Hans ; SEHGELMEBLE, Fernando ; BYLUND, Johan ; ERSMARK, Karolina ; KALAYANOV, Gennadiy ; WÄHLING, Horst ; SALVADOR ODEN, Lourdes</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP3328859A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2018</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KUHN, Cyrille</creatorcontrib><creatorcontrib>AYESA, Susana</creatorcontrib><creatorcontrib>LEIJONMARCK, Marie</creatorcontrib><creatorcontrib>GHIRO, Elise</creatorcontrib><creatorcontrib>BERTRAND, Megan</creatorcontrib><creatorcontrib>STURINO, Claudio</creatorcontrib><creatorcontrib>BROCHU, Christian</creatorcontrib><creatorcontrib>WESTERLIND, Hans</creatorcontrib><creatorcontrib>SEHGELMEBLE, Fernando</creatorcontrib><creatorcontrib>BYLUND, Johan</creatorcontrib><creatorcontrib>ERSMARK, Karolina</creatorcontrib><creatorcontrib>KALAYANOV, Gennadiy</creatorcontrib><creatorcontrib>WÄHLING, Horst</creatorcontrib><creatorcontrib>SALVADOR ODEN, Lourdes</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KUHN, Cyrille</au><au>AYESA, Susana</au><au>LEIJONMARCK, Marie</au><au>GHIRO, Elise</au><au>BERTRAND, Megan</au><au>STURINO, Claudio</au><au>BROCHU, Christian</au><au>WESTERLIND, Hans</au><au>SEHGELMEBLE, Fernando</au><au>BYLUND, Johan</au><au>ERSMARK, Karolina</au><au>KALAYANOV, Gennadiy</au><au>WÄHLING, Horst</au><au>SALVADOR ODEN, Lourdes</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>3-((4-ISOQUINOLIN-3-YL)METHYL)-1H-IMIDAZO[4,5-C]PYRIDIN-2(3H)-ONE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF REPLICATION OF THE RESPIRATORY SYNCYTIAL VIRUS (RSV)</title><date>2018-06-06</date><risdate>2018</risdate><abstract>Compounds of Formula (I): (Formula I), wherein Z1 is NR1A, CHR1A or CR1BR1B; one of Z2 and Z3 is CH or CR1A', the other is N, CH or CR1A'; n is 0, 1 or 2; q is 0, 1 or 2; R1A, R1A', R1B, R2 and R3 are as defined herein, their use as inhibitors of RSV and related aspects.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 3-((4-ISOQUINOLIN-3-YL)METHYL)-1H-IMIDAZO[4,5-C]PYRIDIN-2(3H)-ONE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF REPLICATION OF THE RESPIRATORY SYNCYTIAL VIRUS (RSV) |
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