PHILLYGENIN GLUCURONIC ACID DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF

The present invention provides a novel phillygenin glucuronic acid derivative shown as a general formula (I). wherein, R 1 =H, R 2= C n H 2n+1 , R 3 =C n H 2n+1 or R 1 =C n H 2n+1 , R 2 =C n H 2n+1 , R 3 =H or R 1 -R 2 =-CH 2 -, R 3 =C n H 2n+1 ; n=1-30. The present invention further relates to a pr...

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Hauptverfasser: ZHANG, Yu, JIANG, Renwu, FU, Li, LIU, Zhengxian, FAN, Hongyu, WANG, Kaiqian
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creator ZHANG, Yu
JIANG, Renwu
FU, Li
LIU, Zhengxian
FAN, Hongyu
WANG, Kaiqian
description The present invention provides a novel phillygenin glucuronic acid derivative shown as a general formula (I). wherein, R 1 =H, R 2= C n H 2n+1 , R 3 =C n H 2n+1 or R 1 =C n H 2n+1 , R 2 =C n H 2n+1 , R 3 =H or R 1 -R 2 =-CH 2 -, R 3 =C n H 2n+1 ; n=1-30. The present invention further relates to a preparation method of the compound, a pharmaceutical composition taking the compound as an active ingredient, as well as application of the compound in the present invention in antiviral diseases.
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subjects CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
title PHILLYGENIN GLUCURONIC ACID DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF
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