ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO FLT3 PROTEINS

Antibody drug conjugates (ADC's) that bind to FLT3 protein and variants thereof are described herein. FLT3 exhibits a distinct and limited expression pattern in normal adult tissue(s), and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention pr...

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Hauptverfasser: LIU, Gao, RUDRA-GANGULY, Nandini, MOON, Sung Ju, LOWE, Christine, VIRATA, Cyrus, MALIK, Faisal Hayat, AVINA, Hector, CAPO, Linnette, SNYDER, Josh
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creator LIU, Gao
RUDRA-GANGULY, Nandini
MOON, Sung Ju
LOWE, Christine
VIRATA, Cyrus
MALIK, Faisal Hayat
AVINA, Hector
CAPO, Linnette
SNYDER, Josh
description Antibody drug conjugates (ADC's) that bind to FLT3 protein and variants thereof are described herein. FLT3 exhibits a distinct and limited expression pattern in normal adult tissue(s), and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO FLT3 PROTEINS
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