SOLID FORMS OF AN ASK1 INHIBITOR

Crystalline forms of 5-(4-cyclopropyl-1H-imidazol-1-yl)-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-2-fluoro-4-methylbenzamide (Compound I) were prepared and characterized in the solid state:Also provided are processes of manufacture and methods of using the crystalline forms.

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Hauptverfasser: CHIU, Anna, ANDRES, Mark, CHAN, Brenda, J. Burke, LAPINA, Olga, Viktorovna, YU, Lok, Him, CARRA, Ernest, A, SMOLENSKAYA, Valeriya, LATHROP, Stephen, P, NOTTE, Gregory
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creator CHIU, Anna
ANDRES, Mark
CHAN, Brenda, J. Burke
LAPINA, Olga, Viktorovna
YU, Lok, Him
CARRA, Ernest, A
SMOLENSKAYA, Valeriya
LATHROP, Stephen, P
NOTTE, Gregory
description Crystalline forms of 5-(4-cyclopropyl-1H-imidazol-1-yl)-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-2-fluoro-4-methylbenzamide (Compound I) were prepared and characterized in the solid state:Also provided are processes of manufacture and methods of using the crystalline forms.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title SOLID FORMS OF AN ASK1 INHIBITOR
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