INHIBITORS OF HIF PROLYL HYDROXYLASE

INHIBITORS OF HIF PROLYL HYDROXYLASE

The present invention concerns compounds of formula I or pharmaceutically acceptable salts thereof, which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such...

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Hauptverfasser: WANG, Liping, CRESPO, Alejandro, CAI, Jiaqiang, KOTHANDARAMAN, Shankaran, DU, Xiaoxing, DUBOIS, Byron Gabriel, LIU, Rongqiang, QUAN, Weiguo, SINZ, Christopher, GUIADEEN, Deodialsingh, LIU, Ping
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Sprache:eng ; fre ; ger
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator WANG, Liping
CRESPO, Alejandro
CAI, Jiaqiang
KOTHANDARAMAN, Shankaran
DU, Xiaoxing
DUBOIS, Byron Gabriel
LIU, Rongqiang
QUAN, Weiguo
SINZ, Christopher
GUIADEEN, Deodialsingh
LIU, Ping
description The present invention concerns compounds of formula I or pharmaceutically acceptable salts thereof, which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such as anemia and like conditions, as well as pharmaceutical compositions comprising such a compound and a pharmaceutical carrier.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title INHIBITORS OF HIF PROLYL HYDROXYLASE
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