ARGININE DEIMINASE WITH REDUCED CROSS-REACTIVITY TOWARD ADI - PEG 20 ANTIBODIES FOR CANCER TREATMENT

The present invention relates generally to isolated to arginine deiminase (ADI) proteins that have reduced cross-reactivity with anti-ADI-PEG 20 antibodies as compared to ADI-PEG 20, but which can have functional characteristics comparable to or better than ADI-PEG 20, compositions comprising the AD...

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Bibliographische Detailangaben
Hauptverfasser: THOMSON, James A, SISSON, Wes, SHOWALTER, Richard, LEE, Yang, CHEN, Li-Chang, ALMASSY, Robert, SHIA, Wei-Jong
Format: Patent
Sprache:eng ; fre ; ger
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