INHIBITORS OF INFLUENZA VIRUSES REPLICATION
Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a c...
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| creator | WANG, Tiansheng LEDEBOER, Mark, W LEDFORD, Brian WANNAMAKER, M., Woods BANDARAGE, Upul, K DUFFY, John, P LIN, Chao GERMANN, Ursula, A SALITURO, Francesco G COURT, John, J GAO, Huai KENNEDY, Joseph, M CLARK, Michael, P MALTAIS, Francois JONES, Steven KWONG, Ann Dak-Yee JACOBS, Dylan, H GU, Wenxin PEROLA, Emanuele FARMER, Luc BYRN, Randal DENG, Hongbo ZHOU, Yi CHARIFSON, Paul JIANG, Min DRUTU, Ioana BETHIEL, Randy, S |
| description | Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a compound represented by Structural Formula ( I ):
or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A compound is represented by Structural Formula ( IA ) or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula ( IA ) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle. |
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or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A compound is represented by Structural Formula ( IA ) or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula ( IA ) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle.</description><language>eng ; fre ; ger</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190313&DB=EPODOC&CC=EP&NR=3141252B8$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190313&DB=EPODOC&CC=EP&NR=3141252B8$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WANG, Tiansheng</creatorcontrib><creatorcontrib>LEDEBOER, Mark, W</creatorcontrib><creatorcontrib>LEDFORD, Brian</creatorcontrib><creatorcontrib>WANNAMAKER, M., Woods</creatorcontrib><creatorcontrib>BANDARAGE, Upul, K</creatorcontrib><creatorcontrib>DUFFY, John, P</creatorcontrib><creatorcontrib>LIN, Chao</creatorcontrib><creatorcontrib>GERMANN, Ursula, A</creatorcontrib><creatorcontrib>SALITURO, Francesco G</creatorcontrib><creatorcontrib>COURT, John, J</creatorcontrib><creatorcontrib>GAO, Huai</creatorcontrib><creatorcontrib>KENNEDY, Joseph, M</creatorcontrib><creatorcontrib>CLARK, Michael, P</creatorcontrib><creatorcontrib>MALTAIS, Francois</creatorcontrib><creatorcontrib>JONES, Steven</creatorcontrib><creatorcontrib>KWONG, Ann Dak-Yee</creatorcontrib><creatorcontrib>JACOBS, Dylan, H</creatorcontrib><creatorcontrib>GU, Wenxin</creatorcontrib><creatorcontrib>PEROLA, Emanuele</creatorcontrib><creatorcontrib>FARMER, Luc</creatorcontrib><creatorcontrib>BYRN, Randal</creatorcontrib><creatorcontrib>DENG, Hongbo</creatorcontrib><creatorcontrib>ZHOU, Yi</creatorcontrib><creatorcontrib>CHARIFSON, Paul</creatorcontrib><creatorcontrib>JIANG, Min</creatorcontrib><creatorcontrib>DRUTU, Ioana</creatorcontrib><creatorcontrib>BETHIEL, Randy, S</creatorcontrib><title>INHIBITORS OF INFLUENZA VIRUSES REPLICATION</title><description>Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a compound represented by Structural Formula ( I ):
or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A compound is represented by Structural Formula ( IA ) or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula ( IA ) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZND29PPwdPIM8Q8KVvB3U_D0c_MJdfWLclQI8wwKDXYNVghyDfDxdHYM8fT342FgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8a4BxoYmhkamRk4WxkQoAQBPJCTV</recordid><startdate>20190313</startdate><enddate>20190313</enddate><creator>WANG, Tiansheng</creator><creator>LEDEBOER, Mark, W</creator><creator>LEDFORD, Brian</creator><creator>WANNAMAKER, M., Woods</creator><creator>BANDARAGE, Upul, K</creator><creator>DUFFY, John, P</creator><creator>LIN, Chao</creator><creator>GERMANN, Ursula, A</creator><creator>SALITURO, Francesco G</creator><creator>COURT, John, J</creator><creator>GAO, Huai</creator><creator>KENNEDY, Joseph, M</creator><creator>CLARK, Michael, P</creator><creator>MALTAIS, Francois</creator><creator>JONES, Steven</creator><creator>KWONG, Ann Dak-Yee</creator><creator>JACOBS, Dylan, H</creator><creator>GU, Wenxin</creator><creator>PEROLA, Emanuele</creator><creator>FARMER, Luc</creator><creator>BYRN, Randal</creator><creator>DENG, Hongbo</creator><creator>ZHOU, Yi</creator><creator>CHARIFSON, Paul</creator><creator>JIANG, Min</creator><creator>DRUTU, Ioana</creator><creator>BETHIEL, Randy, S</creator><scope>EVB</scope></search><sort><creationdate>20190313</creationdate><title>INHIBITORS OF INFLUENZA VIRUSES REPLICATION</title><author>WANG, Tiansheng ; LEDEBOER, Mark, W ; LEDFORD, Brian ; WANNAMAKER, M., Woods ; BANDARAGE, Upul, K ; DUFFY, John, P ; LIN, Chao ; GERMANN, Ursula, A ; SALITURO, Francesco G ; COURT, John, J ; GAO, Huai ; KENNEDY, Joseph, M ; CLARK, Michael, P ; MALTAIS, Francois ; JONES, Steven ; KWONG, Ann Dak-Yee ; JACOBS, Dylan, H ; GU, Wenxin ; PEROLA, Emanuele ; FARMER, Luc ; BYRN, Randal ; DENG, Hongbo ; ZHOU, Yi ; CHARIFSON, Paul ; JIANG, Min ; DRUTU, Ioana ; BETHIEL, Randy, S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP3141252B83</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2019</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>WANG, Tiansheng</creatorcontrib><creatorcontrib>LEDEBOER, Mark, W</creatorcontrib><creatorcontrib>LEDFORD, Brian</creatorcontrib><creatorcontrib>WANNAMAKER, M., Woods</creatorcontrib><creatorcontrib>BANDARAGE, Upul, K</creatorcontrib><creatorcontrib>DUFFY, John, P</creatorcontrib><creatorcontrib>LIN, Chao</creatorcontrib><creatorcontrib>GERMANN, Ursula, A</creatorcontrib><creatorcontrib>SALITURO, Francesco G</creatorcontrib><creatorcontrib>COURT, John, J</creatorcontrib><creatorcontrib>GAO, Huai</creatorcontrib><creatorcontrib>KENNEDY, Joseph, M</creatorcontrib><creatorcontrib>CLARK, Michael, P</creatorcontrib><creatorcontrib>MALTAIS, Francois</creatorcontrib><creatorcontrib>JONES, Steven</creatorcontrib><creatorcontrib>KWONG, Ann Dak-Yee</creatorcontrib><creatorcontrib>JACOBS, Dylan, H</creatorcontrib><creatorcontrib>GU, Wenxin</creatorcontrib><creatorcontrib>PEROLA, Emanuele</creatorcontrib><creatorcontrib>FARMER, Luc</creatorcontrib><creatorcontrib>BYRN, Randal</creatorcontrib><creatorcontrib>DENG, Hongbo</creatorcontrib><creatorcontrib>ZHOU, Yi</creatorcontrib><creatorcontrib>CHARIFSON, Paul</creatorcontrib><creatorcontrib>JIANG, Min</creatorcontrib><creatorcontrib>DRUTU, Ioana</creatorcontrib><creatorcontrib>BETHIEL, Randy, S</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>WANG, Tiansheng</au><au>LEDEBOER, Mark, W</au><au>LEDFORD, Brian</au><au>WANNAMAKER, M., Woods</au><au>BANDARAGE, Upul, K</au><au>DUFFY, John, P</au><au>LIN, Chao</au><au>GERMANN, Ursula, A</au><au>SALITURO, Francesco G</au><au>COURT, John, J</au><au>GAO, Huai</au><au>KENNEDY, Joseph, M</au><au>CLARK, Michael, P</au><au>MALTAIS, Francois</au><au>JONES, Steven</au><au>KWONG, Ann Dak-Yee</au><au>JACOBS, Dylan, H</au><au>GU, Wenxin</au><au>PEROLA, Emanuele</au><au>FARMER, Luc</au><au>BYRN, Randal</au><au>DENG, Hongbo</au><au>ZHOU, Yi</au><au>CHARIFSON, Paul</au><au>JIANG, Min</au><au>DRUTU, Ioana</au><au>BETHIEL, Randy, S</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>INHIBITORS OF INFLUENZA VIRUSES REPLICATION</title><date>2019-03-13</date><risdate>2019</risdate><abstract>Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a compound represented by Structural Formula ( I ):
or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A compound is represented by Structural Formula ( IA ) or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula ( IA ) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | INHIBITORS OF INFLUENZA VIRUSES REPLICATION |
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