MOLECULAR DIAGNOSTIC TEST FOR PREDICTING RESPONSE TO ANTI-ANGIOGENIC DRUGS AND PROGNOSIS OF CANCER
Methods for selecting whether to administer an anti-angiogenic therapeutic agent to a subject include steps of measuring the expression levels of one or more biomarkers selected from Table 2 or Table 3 in a sample from the subject; assessing from the expression levels of the one or more biomarkers w...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre ; ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | JELLEMA, Gera PATTERSON, Fionnuala DEHARO, Steve DAVISON, Timothy DONEGAN, Sinead GOURLEY, Charlie MCCAVIGAN, Andrena HILL, Laura A HARKIN, Denis Paul KENNEDY, Richard KEATING, Katherine E |
| description | Methods for selecting whether to administer an anti-angiogenic therapeutic agent to a subject include steps of measuring the expression levels of one or more biomarkers selected from Table 2 or Table 3 in a sample from the subject; assessing from the expression levels of the one or more biomarkers whether the sample from the subject is positive or negative for a biomarker signature, wherein if the sample is positive for the biomarker signature an anti-angiogenic therapeutic agent is contraindicated. Related prognostic methods and treatment methods are also provided. The invention is particularly applicable in ovarian and colorectal cancers. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP3102700A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP3102700A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP3102700A13</originalsourceid><addsrcrecordid>eNqNjEEKwjAQRbtxIeod5gKF1i5ch2QSB-pMSKbrUiWuRAv1_ljBA7h68Hn_bavrRXq0Q28SODKBJStZUMwKXhLEhI6sEgdImKNwRlABw0q14UASkFffpSHkdXXrQb4RyiAerGGLaV9t7tNjKYcfdxV4VHuuy_wayzJPt_Is7xFj1zbHU9OYtvtD-QCO7DOA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>MOLECULAR DIAGNOSTIC TEST FOR PREDICTING RESPONSE TO ANTI-ANGIOGENIC DRUGS AND PROGNOSIS OF CANCER</title><source>esp@cenet</source><creator>JELLEMA, Gera ; PATTERSON, Fionnuala ; DEHARO, Steve ; DAVISON, Timothy ; DONEGAN, Sinead ; GOURLEY, Charlie ; MCCAVIGAN, Andrena ; HILL, Laura A ; HARKIN, Denis Paul ; KENNEDY, Richard ; KEATING, Katherine E</creator><creatorcontrib>JELLEMA, Gera ; PATTERSON, Fionnuala ; DEHARO, Steve ; DAVISON, Timothy ; DONEGAN, Sinead ; GOURLEY, Charlie ; MCCAVIGAN, Andrena ; HILL, Laura A ; HARKIN, Denis Paul ; KENNEDY, Richard ; KEATING, Katherine E</creatorcontrib><description>Methods for selecting whether to administer an anti-angiogenic therapeutic agent to a subject include steps of measuring the expression levels of one or more biomarkers selected from Table 2 or Table 3 in a sample from the subject; assessing from the expression levels of the one or more biomarkers whether the sample from the subject is positive or negative for a biomarker signature, wherein if the sample is positive for the biomarker signature an anti-angiogenic therapeutic agent is contraindicated. Related prognostic methods and treatment methods are also provided. The invention is particularly applicable in ovarian and colorectal cancers.</description><language>eng ; fre ; ger</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; ENZYMOLOGY ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20161214&DB=EPODOC&CC=EP&NR=3102700A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20161214&DB=EPODOC&CC=EP&NR=3102700A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>JELLEMA, Gera</creatorcontrib><creatorcontrib>PATTERSON, Fionnuala</creatorcontrib><creatorcontrib>DEHARO, Steve</creatorcontrib><creatorcontrib>DAVISON, Timothy</creatorcontrib><creatorcontrib>DONEGAN, Sinead</creatorcontrib><creatorcontrib>GOURLEY, Charlie</creatorcontrib><creatorcontrib>MCCAVIGAN, Andrena</creatorcontrib><creatorcontrib>HILL, Laura A</creatorcontrib><creatorcontrib>HARKIN, Denis Paul</creatorcontrib><creatorcontrib>KENNEDY, Richard</creatorcontrib><creatorcontrib>KEATING, Katherine E</creatorcontrib><title>MOLECULAR DIAGNOSTIC TEST FOR PREDICTING RESPONSE TO ANTI-ANGIOGENIC DRUGS AND PROGNOSIS OF CANCER</title><description>Methods for selecting whether to administer an anti-angiogenic therapeutic agent to a subject include steps of measuring the expression levels of one or more biomarkers selected from Table 2 or Table 3 in a sample from the subject; assessing from the expression levels of the one or more biomarkers whether the sample from the subject is positive or negative for a biomarker signature, wherein if the sample is positive for the biomarker signature an anti-angiogenic therapeutic agent is contraindicated. Related prognostic methods and treatment methods are also provided. The invention is particularly applicable in ovarian and colorectal cancers.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>ENZYMOLOGY</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2016</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjEEKwjAQRbtxIeod5gKF1i5ch2QSB-pMSKbrUiWuRAv1_ljBA7h68Hn_bavrRXq0Q28SODKBJStZUMwKXhLEhI6sEgdImKNwRlABw0q14UASkFffpSHkdXXrQb4RyiAerGGLaV9t7tNjKYcfdxV4VHuuy_wayzJPt_Is7xFj1zbHU9OYtvtD-QCO7DOA</recordid><startdate>20161214</startdate><enddate>20161214</enddate><creator>JELLEMA, Gera</creator><creator>PATTERSON, Fionnuala</creator><creator>DEHARO, Steve</creator><creator>DAVISON, Timothy</creator><creator>DONEGAN, Sinead</creator><creator>GOURLEY, Charlie</creator><creator>MCCAVIGAN, Andrena</creator><creator>HILL, Laura A</creator><creator>HARKIN, Denis Paul</creator><creator>KENNEDY, Richard</creator><creator>KEATING, Katherine E</creator><scope>EVB</scope></search><sort><creationdate>20161214</creationdate><title>MOLECULAR DIAGNOSTIC TEST FOR PREDICTING RESPONSE TO ANTI-ANGIOGENIC DRUGS AND PROGNOSIS OF CANCER</title><author>JELLEMA, Gera ; PATTERSON, Fionnuala ; DEHARO, Steve ; DAVISON, Timothy ; DONEGAN, Sinead ; GOURLEY, Charlie ; MCCAVIGAN, Andrena ; HILL, Laura A ; HARKIN, Denis Paul ; KENNEDY, Richard ; KEATING, Katherine E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP3102700A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2016</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>ENZYMOLOGY</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>JELLEMA, Gera</creatorcontrib><creatorcontrib>PATTERSON, Fionnuala</creatorcontrib><creatorcontrib>DEHARO, Steve</creatorcontrib><creatorcontrib>DAVISON, Timothy</creatorcontrib><creatorcontrib>DONEGAN, Sinead</creatorcontrib><creatorcontrib>GOURLEY, Charlie</creatorcontrib><creatorcontrib>MCCAVIGAN, Andrena</creatorcontrib><creatorcontrib>HILL, Laura A</creatorcontrib><creatorcontrib>HARKIN, Denis Paul</creatorcontrib><creatorcontrib>KENNEDY, Richard</creatorcontrib><creatorcontrib>KEATING, Katherine E</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>JELLEMA, Gera</au><au>PATTERSON, Fionnuala</au><au>DEHARO, Steve</au><au>DAVISON, Timothy</au><au>DONEGAN, Sinead</au><au>GOURLEY, Charlie</au><au>MCCAVIGAN, Andrena</au><au>HILL, Laura A</au><au>HARKIN, Denis Paul</au><au>KENNEDY, Richard</au><au>KEATING, Katherine E</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>MOLECULAR DIAGNOSTIC TEST FOR PREDICTING RESPONSE TO ANTI-ANGIOGENIC DRUGS AND PROGNOSIS OF CANCER</title><date>2016-12-14</date><risdate>2016</risdate><abstract>Methods for selecting whether to administer an anti-angiogenic therapeutic agent to a subject include steps of measuring the expression levels of one or more biomarkers selected from Table 2 or Table 3 in a sample from the subject; assessing from the expression levels of the one or more biomarkers whether the sample from the subject is positive or negative for a biomarker signature, wherein if the sample is positive for the biomarker signature an anti-angiogenic therapeutic agent is contraindicated. Related prognostic methods and treatment methods are also provided. The invention is particularly applicable in ovarian and colorectal cancers.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre ; ger |
| recordid | cdi_epo_espacenet_EP3102700A1 |
| source | esp@cenet |
| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE |
| title | MOLECULAR DIAGNOSTIC TEST FOR PREDICTING RESPONSE TO ANTI-ANGIOGENIC DRUGS AND PROGNOSIS OF CANCER |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-10T21%3A10%3A06IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=JELLEMA,%20Gera&rft.date=2016-12-14&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP3102700A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |