ABUSE AND MISUSE DETERRENT TRANSDERMAL SYSTEMS

ABUSE AND MISUSE DETERRENT TRANSDERMAL SYSTEMS

An abuse deterrent and misuse deterrent transdermal patch comprising aversive agents incorporated in the backing layer of the patch. The aversive agents can exhibit biphasic or sustained kinetics of release with an immediate portion released rapidly and an extended portion released in a prolonged ma...

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Hauptverfasser: DAMON, Steven, Paul, GAULDING, Jeffrey, C, ENSCORE, David, James, SMITH, Alan, TAGLIAFERRI, Frank
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator DAMON, Steven, Paul
GAULDING, Jeffrey, C
ENSCORE, David, James
SMITH, Alan
TAGLIAFERRI, Frank
description An abuse deterrent and misuse deterrent transdermal patch comprising aversive agents incorporated in the backing layer of the patch. The aversive agents can exhibit biphasic or sustained kinetics of release with an immediate portion released rapidly and an extended portion released in a prolonged manner when exposed to a dissolution medium. The prolonged aversive agent release provides deterrence against extraction of drug from fresh and used patches and serves to prevent accidental misuse of used patches by children. The abuse deterrent and misuse deterrent patch systems can be used for transdermal delivery of therapeutically active agents and particularly those drugs that are highly prone to abuse such as opiate and opioid analgesics and stimulants.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title ABUSE AND MISUSE DETERRENT TRANSDERMAL SYSTEMS
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