ANTIDIABETIC TRICYCLIC COMPOUNDS
Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the prese...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre ; ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | NARGUND, Ravi COLLETTI, Steven L BIFTU, Tesfaye KAR, Nam Fung BIJU, Purakkatle SPERBECK, Donald M NAIR, Anilkumar ZHU, Chen HU, Bin CUI, Mingxiang JOSIEN, Hubert HAGMANN, William K |
| description | Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslip idemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP3055288A4</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP3055288A4</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP3055288A43</originalsourceid><addsrcrecordid>eNrjZFBw9AvxdPF0dHIN8XRWCAnydI509gGynP19A_xD_VyCeRhY0xJzilN5oTQ3g4Kba4izh25qQX58anFBYnJqXmpJvGuAsYGpqZGFhaOJMRFKAMLXIbI</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>ANTIDIABETIC TRICYCLIC COMPOUNDS</title><source>esp@cenet</source><creator>NARGUND, Ravi ; COLLETTI, Steven L ; BIFTU, Tesfaye ; KAR, Nam Fung ; BIJU, Purakkatle ; SPERBECK, Donald M ; NAIR, Anilkumar ; ZHU, Chen ; HU, Bin ; CUI, Mingxiang ; JOSIEN, Hubert ; HAGMANN, William K</creator><creatorcontrib>NARGUND, Ravi ; COLLETTI, Steven L ; BIFTU, Tesfaye ; KAR, Nam Fung ; BIJU, Purakkatle ; SPERBECK, Donald M ; NAIR, Anilkumar ; ZHU, Chen ; HU, Bin ; CUI, Mingxiang ; JOSIEN, Hubert ; HAGMANN, William K</creatorcontrib><description>Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslip idemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170315&DB=EPODOC&CC=EP&NR=3055288A4$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170315&DB=EPODOC&CC=EP&NR=3055288A4$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>NARGUND, Ravi</creatorcontrib><creatorcontrib>COLLETTI, Steven L</creatorcontrib><creatorcontrib>BIFTU, Tesfaye</creatorcontrib><creatorcontrib>KAR, Nam Fung</creatorcontrib><creatorcontrib>BIJU, Purakkatle</creatorcontrib><creatorcontrib>SPERBECK, Donald M</creatorcontrib><creatorcontrib>NAIR, Anilkumar</creatorcontrib><creatorcontrib>ZHU, Chen</creatorcontrib><creatorcontrib>HU, Bin</creatorcontrib><creatorcontrib>CUI, Mingxiang</creatorcontrib><creatorcontrib>JOSIEN, Hubert</creatorcontrib><creatorcontrib>HAGMANN, William K</creatorcontrib><title>ANTIDIABETIC TRICYCLIC COMPOUNDS</title><description>Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslip idemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2017</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFBw9AvxdPF0dHIN8XRWCAnydI509gGynP19A_xD_VyCeRhY0xJzilN5oTQ3g4Kba4izh25qQX58anFBYnJqXmpJvGuAsYGpqZGFhaOJMRFKAMLXIbI</recordid><startdate>20170315</startdate><enddate>20170315</enddate><creator>NARGUND, Ravi</creator><creator>COLLETTI, Steven L</creator><creator>BIFTU, Tesfaye</creator><creator>KAR, Nam Fung</creator><creator>BIJU, Purakkatle</creator><creator>SPERBECK, Donald M</creator><creator>NAIR, Anilkumar</creator><creator>ZHU, Chen</creator><creator>HU, Bin</creator><creator>CUI, Mingxiang</creator><creator>JOSIEN, Hubert</creator><creator>HAGMANN, William K</creator><scope>EVB</scope></search><sort><creationdate>20170315</creationdate><title>ANTIDIABETIC TRICYCLIC COMPOUNDS</title><author>NARGUND, Ravi ; COLLETTI, Steven L ; BIFTU, Tesfaye ; KAR, Nam Fung ; BIJU, Purakkatle ; SPERBECK, Donald M ; NAIR, Anilkumar ; ZHU, Chen ; HU, Bin ; CUI, Mingxiang ; JOSIEN, Hubert ; HAGMANN, William K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP3055288A43</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2017</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>NARGUND, Ravi</creatorcontrib><creatorcontrib>COLLETTI, Steven L</creatorcontrib><creatorcontrib>BIFTU, Tesfaye</creatorcontrib><creatorcontrib>KAR, Nam Fung</creatorcontrib><creatorcontrib>BIJU, Purakkatle</creatorcontrib><creatorcontrib>SPERBECK, Donald M</creatorcontrib><creatorcontrib>NAIR, Anilkumar</creatorcontrib><creatorcontrib>ZHU, Chen</creatorcontrib><creatorcontrib>HU, Bin</creatorcontrib><creatorcontrib>CUI, Mingxiang</creatorcontrib><creatorcontrib>JOSIEN, Hubert</creatorcontrib><creatorcontrib>HAGMANN, William K</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>NARGUND, Ravi</au><au>COLLETTI, Steven L</au><au>BIFTU, Tesfaye</au><au>KAR, Nam Fung</au><au>BIJU, Purakkatle</au><au>SPERBECK, Donald M</au><au>NAIR, Anilkumar</au><au>ZHU, Chen</au><au>HU, Bin</au><au>CUI, Mingxiang</au><au>JOSIEN, Hubert</au><au>HAGMANN, William K</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANTIDIABETIC TRICYCLIC COMPOUNDS</title><date>2017-03-15</date><risdate>2017</risdate><abstract>Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslip idemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre ; ger |
| recordid | cdi_epo_espacenet_EP3055288A4 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | ANTIDIABETIC TRICYCLIC COMPOUNDS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T12%3A55%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=NARGUND,%20Ravi&rft.date=2017-03-15&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP3055288A4%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |