ORAL PHARMACEUTICAL FORMULATION OF OMARIGLIPTIN

The present invention is directed to stable, oral pharmaceutical formulations of dipeptidyl peptidase-4 inhibitors, such as omarigliptin. Such pharmaceutical formulations comprise omarigliptin; and neutral excipients, wherein the neutral excipient is present in the amount of at least 75% by weight o...

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Hauptverfasser: COOPER, Vincent, Brett, GUPTA, Rajan, PYGALL, Samuel, Robert, BRADLEY, Kathryn, Alanna, STANFORD, Madison, Paige, XIE, Lin
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creator COOPER, Vincent, Brett
GUPTA, Rajan
PYGALL, Samuel, Robert
BRADLEY, Kathryn, Alanna
STANFORD, Madison, Paige
XIE, Lin
description The present invention is directed to stable, oral pharmaceutical formulations of dipeptidyl peptidase-4 inhibitors, such as omarigliptin. Such pharmaceutical formulations comprise omarigliptin; and neutral excipients, wherein the neutral excipient is present in the amount of at least 75% by weight of the pharmaceutical formulation and comprises at least one non-reducible sugar diluent or a mixture of non-reducible sugar diluents.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title ORAL PHARMACEUTICAL FORMULATION OF OMARIGLIPTIN
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