COMPOSITION CONTAINING MONOACETYLDIACYLGLYCEROL COMPOUND AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES
The present invention relates to a pharmaceutical composition containing a monoacetyldiacylglycerol compound as an active ingredient for preventing or treating chronic obstructive pulmonary diseases, and a functional health food composition for treating or preventing chronic obstructive pulmonary di...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre ; ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | AHN, Kyung Seop KIM, Seung Hyung SOHN, Ki Young KANG, JongKoo KWON, Ok-Kyoung SHIN, In Sik LEE, Su Ui CHUN, Chan Mi LEE, Tae-Suk KIM, Hye Kyung OH, Sei-Ryang HAN, Yong-Hae |
| description | The present invention relates to a pharmaceutical composition containing a monoacetyldiacylglycerol compound as an active ingredient for preventing or treating chronic obstructive pulmonary diseases, and a functional health food composition for treating or preventing chronic obstructive pulmonary diseases. The monoacetyldiacylglycerol compound of the present invention inhibits the IL-4 expression in EL-4 cells and inhibits the infiltration of inflammatory cells into the bronchial tube in an animal model. In addition, the compounds of the present invention have an excellent effect of inhibiting the expression of CXCL-1, TNF-±, or MIP-2, thereby overcoming side effects of the currently used therapeutic agents for chronic obstructive pulmonary diseases, having no toxicity, and exhibiting a superior therapeutic effect, and thus can be useful as a composition for preventing, treating, and alleviating chronic obstructive pulmonary diseases. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP3037093B1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP3037093B1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP3037093B13</originalsourceid><addsrcrecordid>eNqNjUEKwjAURLtxIeod_gWEShfiMv7-th_S_JKkhaxKkbgSLdR7eGVr9QCuZgbezKyTF0rdiGPPYgDFeMWGTQm1GFFIPuicFQZd6oBkRcPCtyYH5UCh545g5i3lTMZDIRYaS93sPytz8pbU4rGyYhhBzs7b9ttsWj0fKRsgZ0fKkdsmq-twm-Lup5sECvJY7eP46OM0Dpd4j8-emizNjukpOx-yP5A3YHxBIA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>COMPOSITION CONTAINING MONOACETYLDIACYLGLYCEROL COMPOUND AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES</title><source>esp@cenet</source><creator>AHN, Kyung Seop ; KIM, Seung Hyung ; SOHN, Ki Young ; KANG, JongKoo ; KWON, Ok-Kyoung ; SHIN, In Sik ; LEE, Su Ui ; CHUN, Chan Mi ; LEE, Tae-Suk ; KIM, Hye Kyung ; OH, Sei-Ryang ; HAN, Yong-Hae</creator><creatorcontrib>AHN, Kyung Seop ; KIM, Seung Hyung ; SOHN, Ki Young ; KANG, JongKoo ; KWON, Ok-Kyoung ; SHIN, In Sik ; LEE, Su Ui ; CHUN, Chan Mi ; LEE, Tae-Suk ; KIM, Hye Kyung ; OH, Sei-Ryang ; HAN, Yong-Hae</creatorcontrib><description>The present invention relates to a pharmaceutical composition containing a monoacetyldiacylglycerol compound as an active ingredient for preventing or treating chronic obstructive pulmonary diseases, and a functional health food composition for treating or preventing chronic obstructive pulmonary diseases. The monoacetyldiacylglycerol compound of the present invention inhibits the IL-4 expression in EL-4 cells and inhibits the infiltration of inflammatory cells into the bronchial tube in an animal model. In addition, the compounds of the present invention have an excellent effect of inhibiting the expression of CXCL-1, TNF-±, or MIP-2, thereby overcoming side effects of the currently used therapeutic agents for chronic obstructive pulmonary diseases, having no toxicity, and exhibiting a superior therapeutic effect, and thus can be useful as a composition for preventing, treating, and alleviating chronic obstructive pulmonary diseases.</description><language>eng ; fre ; ger</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200101&DB=EPODOC&CC=EP&NR=3037093B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200101&DB=EPODOC&CC=EP&NR=3037093B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>AHN, Kyung Seop</creatorcontrib><creatorcontrib>KIM, Seung Hyung</creatorcontrib><creatorcontrib>SOHN, Ki Young</creatorcontrib><creatorcontrib>KANG, JongKoo</creatorcontrib><creatorcontrib>KWON, Ok-Kyoung</creatorcontrib><creatorcontrib>SHIN, In Sik</creatorcontrib><creatorcontrib>LEE, Su Ui</creatorcontrib><creatorcontrib>CHUN, Chan Mi</creatorcontrib><creatorcontrib>LEE, Tae-Suk</creatorcontrib><creatorcontrib>KIM, Hye Kyung</creatorcontrib><creatorcontrib>OH, Sei-Ryang</creatorcontrib><creatorcontrib>HAN, Yong-Hae</creatorcontrib><title>COMPOSITION CONTAINING MONOACETYLDIACYLGLYCEROL COMPOUND AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES</title><description>The present invention relates to a pharmaceutical composition containing a monoacetyldiacylglycerol compound as an active ingredient for preventing or treating chronic obstructive pulmonary diseases, and a functional health food composition for treating or preventing chronic obstructive pulmonary diseases. The monoacetyldiacylglycerol compound of the present invention inhibits the IL-4 expression in EL-4 cells and inhibits the infiltration of inflammatory cells into the bronchial tube in an animal model. In addition, the compounds of the present invention have an excellent effect of inhibiting the expression of CXCL-1, TNF-±, or MIP-2, thereby overcoming side effects of the currently used therapeutic agents for chronic obstructive pulmonary diseases, having no toxicity, and exhibiting a superior therapeutic effect, and thus can be useful as a composition for preventing, treating, and alleviating chronic obstructive pulmonary diseases.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjUEKwjAURLtxIeod_gWEShfiMv7-th_S_JKkhaxKkbgSLdR7eGVr9QCuZgbezKyTF0rdiGPPYgDFeMWGTQm1GFFIPuicFQZd6oBkRcPCtyYH5UCh545g5i3lTMZDIRYaS93sPytz8pbU4rGyYhhBzs7b9ttsWj0fKRsgZ0fKkdsmq-twm-Lup5sECvJY7eP46OM0Dpd4j8-emizNjukpOx-yP5A3YHxBIA</recordid><startdate>20200101</startdate><enddate>20200101</enddate><creator>AHN, Kyung Seop</creator><creator>KIM, Seung Hyung</creator><creator>SOHN, Ki Young</creator><creator>KANG, JongKoo</creator><creator>KWON, Ok-Kyoung</creator><creator>SHIN, In Sik</creator><creator>LEE, Su Ui</creator><creator>CHUN, Chan Mi</creator><creator>LEE, Tae-Suk</creator><creator>KIM, Hye Kyung</creator><creator>OH, Sei-Ryang</creator><creator>HAN, Yong-Hae</creator><scope>EVB</scope></search><sort><creationdate>20200101</creationdate><title>COMPOSITION CONTAINING MONOACETYLDIACYLGLYCEROL COMPOUND AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES</title><author>AHN, Kyung Seop ; KIM, Seung Hyung ; SOHN, Ki Young ; KANG, JongKoo ; KWON, Ok-Kyoung ; SHIN, In Sik ; LEE, Su Ui ; CHUN, Chan Mi ; LEE, Tae-Suk ; KIM, Hye Kyung ; OH, Sei-Ryang ; HAN, Yong-Hae</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP3037093B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2020</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>AHN, Kyung Seop</creatorcontrib><creatorcontrib>KIM, Seung Hyung</creatorcontrib><creatorcontrib>SOHN, Ki Young</creatorcontrib><creatorcontrib>KANG, JongKoo</creatorcontrib><creatorcontrib>KWON, Ok-Kyoung</creatorcontrib><creatorcontrib>SHIN, In Sik</creatorcontrib><creatorcontrib>LEE, Su Ui</creatorcontrib><creatorcontrib>CHUN, Chan Mi</creatorcontrib><creatorcontrib>LEE, Tae-Suk</creatorcontrib><creatorcontrib>KIM, Hye Kyung</creatorcontrib><creatorcontrib>OH, Sei-Ryang</creatorcontrib><creatorcontrib>HAN, Yong-Hae</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>AHN, Kyung Seop</au><au>KIM, Seung Hyung</au><au>SOHN, Ki Young</au><au>KANG, JongKoo</au><au>KWON, Ok-Kyoung</au><au>SHIN, In Sik</au><au>LEE, Su Ui</au><au>CHUN, Chan Mi</au><au>LEE, Tae-Suk</au><au>KIM, Hye Kyung</au><au>OH, Sei-Ryang</au><au>HAN, Yong-Hae</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>COMPOSITION CONTAINING MONOACETYLDIACYLGLYCEROL COMPOUND AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES</title><date>2020-01-01</date><risdate>2020</risdate><abstract>The present invention relates to a pharmaceutical composition containing a monoacetyldiacylglycerol compound as an active ingredient for preventing or treating chronic obstructive pulmonary diseases, and a functional health food composition for treating or preventing chronic obstructive pulmonary diseases. The monoacetyldiacylglycerol compound of the present invention inhibits the IL-4 expression in EL-4 cells and inhibits the infiltration of inflammatory cells into the bronchial tube in an animal model. In addition, the compounds of the present invention have an excellent effect of inhibiting the expression of CXCL-1, TNF-±, or MIP-2, thereby overcoming side effects of the currently used therapeutic agents for chronic obstructive pulmonary diseases, having no toxicity, and exhibiting a superior therapeutic effect, and thus can be useful as a composition for preventing, treating, and alleviating chronic obstructive pulmonary diseases.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre ; ger |
| recordid | cdi_epo_espacenet_EP3037093B1 |
| source | esp@cenet |
| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | COMPOSITION CONTAINING MONOACETYLDIACYLGLYCEROL COMPOUND AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-19T18%3A56%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=AHN,%20Kyung%20Seop&rft.date=2020-01-01&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP3037093B1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |