COMPOSITIONS FOR TARGETED DELIVERY OF SIRNA

The present invention is directed compositions for targeted delivery of RNA interference (RNAi) polynucleotides to hepatocytes in vivo. Targeted RNAi polynucleotides are administered together with co-targeted delivery polymers. Delivery polymers provide membrane penetration function for movement of...

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Hauptverfasser: LEWIS, David L, HOFFMANN, Torsten, KITAS, Eric A, MOHR, Peter, WAKEFIELD, Darren H, HADWIGER, Philipp, ROZEMA, David B, THUER, Wilma, VALIS, Linda Christine
Format: Patent
Sprache:eng ; fre ; ger
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