INHIBITORS OF LEUKOTRIENE PRODUCTION

The present invention relates to aryl pyrazoles, and pharmaceutically acceptable salts thereof. The aryl pyrazoles of the present invention are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorders. The present invention also relates to pharmaceutical composit...

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Hauptverfasser: ABEYWARDANE, Asitha, RAZAVI, Hossein, SMITH KEENAN, Lana Louise, BROADWATER, John Alan, BRUNETTE, Steven Richard, KIRRANE, Thomas Martin Jr, ZHANG, Qiang, SIBLEY, Robert
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creator ABEYWARDANE, Asitha
RAZAVI, Hossein
SMITH KEENAN, Lana Louise
BROADWATER, John Alan
BRUNETTE, Steven Richard
KIRRANE, Thomas Martin Jr
ZHANG, Qiang
SIBLEY, Robert
description The present invention relates to aryl pyrazoles, and pharmaceutically acceptable salts thereof. The aryl pyrazoles of the present invention are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorders. The present invention also relates to pharmaceutical compositions comprising the aryl pyrazoles of the present invention, methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title INHIBITORS OF LEUKOTRIENE PRODUCTION
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