ANTIBODY-DRUG CONJUGATE HAVING IMPROVED STABILITY AND USE THEREOF

The present invention relates to: an antibody-drug conjugate having drug conjugated to an N-terminal amino acid residue of a heavy chain or a light chain of an antibody; a preparation method therefor; and a use thereof.

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Hauptverfasser: EOM, Jae Hyun, MOON, Kyung Duk, KIM, Young Min, SONG, Dae Hae, KIM, Jae Yong, KO, Min Ji, JUNG, Jin Won, KIM, Ju Hee
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creator EOM, Jae Hyun
MOON, Kyung Duk
KIM, Young Min
SONG, Dae Hae
KIM, Jae Yong
KO, Min Ji
JUNG, Jin Won
KIM, Ju Hee
description The present invention relates to: an antibody-drug conjugate having drug conjugated to an N-terminal amino acid residue of a heavy chain or a light chain of an antibody; a preparation method therefor; and a use thereof.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title ANTIBODY-DRUG CONJUGATE HAVING IMPROVED STABILITY AND USE THEREOF
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