COMBINATION OF A NALOXOL-PEG CONJUGATE AND AN OPIOID AGONIST

Naloxol-polyethylene glycol conjugates of the formula: are provided in oxalate or phoshate salt forms including crystalline forms. To achieve a central analgesic effect, the conjugates will be administered an opioid agonist.

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Hauptverfasser: AURELL, Carl-Johan, SEBHATU, Tesfai, PARENT, Stephan, ASLUND, Bengt Leonard, JENSEN, David Richard, LECHUGA-BALLESTEROS, David, YMEN, Bo Ingvar, BOHLIN, Martin Hans, HEALY, Eric Thomas, JONAITIS, David Thomas
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creator AURELL, Carl-Johan
SEBHATU, Tesfai
PARENT, Stephan
ASLUND, Bengt Leonard
JENSEN, David Richard
LECHUGA-BALLESTEROS, David
YMEN, Bo Ingvar
BOHLIN, Martin Hans
HEALY, Eric Thomas
JONAITIS, David Thomas
description Naloxol-polyethylene glycol conjugates of the formula: are provided in oxalate or phoshate salt forms including crystalline forms. To achieve a central analgesic effect, the conjugates will be administered an opioid agonist.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title COMBINATION OF A NALOXOL-PEG CONJUGATE AND AN OPIOID AGONIST
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