NON-ADDICTIVE ANALGESIC SUSTAINED-RELEASE DRUG DELIVERY SYSTEM AND PREPARATION METHOD THEREOF

NON-ADDICTIVE ANALGESIC SUSTAINED-RELEASE DRUG DELIVERY SYSTEM AND PREPARATION METHOD THEREOF

The present invention generally relates to a non-addictive anesthetic analgesic sustained-release drug delivery system, and encompasses formulation and preparation processes, dosage forms and use thereof. The drug delivery system according to the present invention is formulated with: (1) an anesthet...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: CHEN, Tao, LU, Wudang, WANG, Weijiao, GAO, Jianli, ZHAO, Qingchuan, KONG, Danfeng, YU, Weiping, WU, Qinyuan
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator CHEN, Tao
LU, Wudang
WANG, Weijiao
GAO, Jianli
ZHAO, Qingchuan
KONG, Danfeng
YU, Weiping
WU, Qinyuan
description The present invention generally relates to a non-addictive anesthetic analgesic sustained-release drug delivery system, and encompasses formulation and preparation processes, dosage forms and use thereof. The drug delivery system according to the present invention is formulated with: (1) an anesthetic analgesic drug as an active compound having a concentration of 1 mg/ml-160 mg/ml, the drug including: a local anesthetic, such as ropivacaine free base, bupivacaine free base, and salts thereof, and a combination of a local anesthetic and a nonsteroidal analgesic and/or an opioid analgesic; (2) a menstruum in a proportion of 1%-75% (v/v), the menstruum including benzyl alcohol, ethanol, benzyl benzoate, ethyl lactate, and tetrahydrofurfuryl polyethylene glycol ether; and (3) a drug sustained-release agent in a proportion of 25%-99% (v/v), the sustained-release agent including natural vegetable oils such as soybean oil, castor oil, and sesame oil, synthetic fats such as ethyl oleate and medium chain oil, artificially modified semi-natural fats and derivatives thereof.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP2949316B1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP2949316B1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP2949316B13</originalsourceid><addsrcrecordid>eNqNy7EOgjAURmEWB6O-w30BBsSYMF7bH2gCLWkvJgyGEFMnoyT4_pHBB3A6y3e2yc06m7LWRom5gthyUyEYRaEPwsZCpx4NOIC07yvSaFbnBwpDELTroKnz6NizGGephdROk9TwcOU-2Tym5xIPv-4SKiGqTuP8HuMyT_f4ip8R3bE4FXl2vmT5H-QLojAyfQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>NON-ADDICTIVE ANALGESIC SUSTAINED-RELEASE DRUG DELIVERY SYSTEM AND PREPARATION METHOD THEREOF</title><source>esp@cenet</source><creator>CHEN, Tao ; LU, Wudang ; WANG, Weijiao ; GAO, Jianli ; ZHAO, Qingchuan ; KONG, Danfeng ; YU, Weiping ; WU, Qinyuan</creator><creatorcontrib>CHEN, Tao ; LU, Wudang ; WANG, Weijiao ; GAO, Jianli ; ZHAO, Qingchuan ; KONG, Danfeng ; YU, Weiping ; WU, Qinyuan</creatorcontrib><description>The present invention generally relates to a non-addictive anesthetic analgesic sustained-release drug delivery system, and encompasses formulation and preparation processes, dosage forms and use thereof. The drug delivery system according to the present invention is formulated with: (1) an anesthetic analgesic drug as an active compound having a concentration of 1 mg/ml-160 mg/ml, the drug including: a local anesthetic, such as ropivacaine free base, bupivacaine free base, and salts thereof, and a combination of a local anesthetic and a nonsteroidal analgesic and/or an opioid analgesic; (2) a menstruum in a proportion of 1%-75% (v/v), the menstruum including benzyl alcohol, ethanol, benzyl benzoate, ethyl lactate, and tetrahydrofurfuryl polyethylene glycol ether; and (3) a drug sustained-release agent in a proportion of 25%-99% (v/v), the sustained-release agent including natural vegetable oils such as soybean oil, castor oil, and sesame oil, synthetic fats such as ethyl oleate and medium chain oil, artificially modified semi-natural fats and derivatives thereof.</description><language>eng ; fre ; ger</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20200701&amp;DB=EPODOC&amp;CC=EP&amp;NR=2949316B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20200701&amp;DB=EPODOC&amp;CC=EP&amp;NR=2949316B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHEN, Tao</creatorcontrib><creatorcontrib>LU, Wudang</creatorcontrib><creatorcontrib>WANG, Weijiao</creatorcontrib><creatorcontrib>GAO, Jianli</creatorcontrib><creatorcontrib>ZHAO, Qingchuan</creatorcontrib><creatorcontrib>KONG, Danfeng</creatorcontrib><creatorcontrib>YU, Weiping</creatorcontrib><creatorcontrib>WU, Qinyuan</creatorcontrib><title>NON-ADDICTIVE ANALGESIC SUSTAINED-RELEASE DRUG DELIVERY SYSTEM AND PREPARATION METHOD THEREOF</title><description>The present invention generally relates to a non-addictive anesthetic analgesic sustained-release drug delivery system, and encompasses formulation and preparation processes, dosage forms and use thereof. The drug delivery system according to the present invention is formulated with: (1) an anesthetic analgesic drug as an active compound having a concentration of 1 mg/ml-160 mg/ml, the drug including: a local anesthetic, such as ropivacaine free base, bupivacaine free base, and salts thereof, and a combination of a local anesthetic and a nonsteroidal analgesic and/or an opioid analgesic; (2) a menstruum in a proportion of 1%-75% (v/v), the menstruum including benzyl alcohol, ethanol, benzyl benzoate, ethyl lactate, and tetrahydrofurfuryl polyethylene glycol ether; and (3) a drug sustained-release agent in a proportion of 25%-99% (v/v), the sustained-release agent including natural vegetable oils such as soybean oil, castor oil, and sesame oil, synthetic fats such as ethyl oleate and medium chain oil, artificially modified semi-natural fats and derivatives thereof.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNy7EOgjAURmEWB6O-w30BBsSYMF7bH2gCLWkvJgyGEFMnoyT4_pHBB3A6y3e2yc06m7LWRom5gthyUyEYRaEPwsZCpx4NOIC07yvSaFbnBwpDELTroKnz6NizGGephdROk9TwcOU-2Tym5xIPv-4SKiGqTuP8HuMyT_f4ip8R3bE4FXl2vmT5H-QLojAyfQ</recordid><startdate>20200701</startdate><enddate>20200701</enddate><creator>CHEN, Tao</creator><creator>LU, Wudang</creator><creator>WANG, Weijiao</creator><creator>GAO, Jianli</creator><creator>ZHAO, Qingchuan</creator><creator>KONG, Danfeng</creator><creator>YU, Weiping</creator><creator>WU, Qinyuan</creator><scope>EVB</scope></search><sort><creationdate>20200701</creationdate><title>NON-ADDICTIVE ANALGESIC SUSTAINED-RELEASE DRUG DELIVERY SYSTEM AND PREPARATION METHOD THEREOF</title><author>CHEN, Tao ; LU, Wudang ; WANG, Weijiao ; GAO, Jianli ; ZHAO, Qingchuan ; KONG, Danfeng ; YU, Weiping ; WU, Qinyuan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP2949316B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2020</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>CHEN, Tao</creatorcontrib><creatorcontrib>LU, Wudang</creatorcontrib><creatorcontrib>WANG, Weijiao</creatorcontrib><creatorcontrib>GAO, Jianli</creatorcontrib><creatorcontrib>ZHAO, Qingchuan</creatorcontrib><creatorcontrib>KONG, Danfeng</creatorcontrib><creatorcontrib>YU, Weiping</creatorcontrib><creatorcontrib>WU, Qinyuan</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CHEN, Tao</au><au>LU, Wudang</au><au>WANG, Weijiao</au><au>GAO, Jianli</au><au>ZHAO, Qingchuan</au><au>KONG, Danfeng</au><au>YU, Weiping</au><au>WU, Qinyuan</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NON-ADDICTIVE ANALGESIC SUSTAINED-RELEASE DRUG DELIVERY SYSTEM AND PREPARATION METHOD THEREOF</title><date>2020-07-01</date><risdate>2020</risdate><abstract>The present invention generally relates to a non-addictive anesthetic analgesic sustained-release drug delivery system, and encompasses formulation and preparation processes, dosage forms and use thereof. The drug delivery system according to the present invention is formulated with: (1) an anesthetic analgesic drug as an active compound having a concentration of 1 mg/ml-160 mg/ml, the drug including: a local anesthetic, such as ropivacaine free base, bupivacaine free base, and salts thereof, and a combination of a local anesthetic and a nonsteroidal analgesic and/or an opioid analgesic; (2) a menstruum in a proportion of 1%-75% (v/v), the menstruum including benzyl alcohol, ethanol, benzyl benzoate, ethyl lactate, and tetrahydrofurfuryl polyethylene glycol ether; and (3) a drug sustained-release agent in a proportion of 25%-99% (v/v), the sustained-release agent including natural vegetable oils such as soybean oil, castor oil, and sesame oil, synthetic fats such as ethyl oleate and medium chain oil, artificially modified semi-natural fats and derivatives thereof.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; fre ; ger
recordid cdi_epo_espacenet_EP2949316B1
source esp@cenet
subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title NON-ADDICTIVE ANALGESIC SUSTAINED-RELEASE DRUG DELIVERY SYSTEM AND PREPARATION METHOD THEREOF
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-10T11%3A45%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=CHEN,%20Tao&rft.date=2020-07-01&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP2949316B1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true