SODIUM CHANNEL BLOCKERS, PREPARATION METHOD THEREOF AND USE THEREOF
The present invention relates to a compound having a blocking effect against sodium ion channels, particularly Nav1.7, a preparation method thereof and the use thereof. A compound represented by formula 1 according to the invention, or a pharmaceutically acceptable salt, hydrate, solvate or isomer t...
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| creator | JUN, SUN AH CHO, MIN JAE LEE, JUN HEE LEE, HYUNG GEUN CHUNG, KYUNG HA KIM, IN WOO NA, YUN SOO YOON, YUN SOO KIM, HA YOUNG KIM, HYO SHIN KIM, JI DUCK |
| description | The present invention relates to a compound having a blocking effect against sodium ion channels, particularly Nav1.7, a preparation method thereof and the use thereof. A compound represented by formula 1 according to the invention, or a pharmaceutically acceptable salt, hydrate, solvate or isomer thereof may be effectively used for the prevention or treatment of pain, for example, acute pain, chronic pain, neuropathic pain, post-surgery pain, migraine, arthralgia, neuropathy, nerve injury, diabetic neuropathy, neuropathic disease, epilepsy, arrhythmia, myotonia, ataxia, multiple sclerosis, irritable bowel syndrome, urinary incontinence, visceral pain, depression, erythromelalgia, or paroxysmal extreme pain disorder (PEPD). |
| format | Patent |
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A compound represented by formula 1 according to the invention, or a pharmaceutically acceptable salt, hydrate, solvate or isomer thereof may be effectively used for the prevention or treatment of pain, for example, acute pain, chronic pain, neuropathic pain, post-surgery pain, migraine, arthralgia, neuropathy, nerve injury, diabetic neuropathy, neuropathic disease, epilepsy, arrhythmia, myotonia, ataxia, multiple sclerosis, irritable bowel syndrome, urinary incontinence, visceral pain, depression, erythromelalgia, or paroxysmal extreme pain disorder (PEPD).</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150819&DB=EPODOC&CC=EP&NR=2906558A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150819&DB=EPODOC&CC=EP&NR=2906558A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>JUN, SUN AH</creatorcontrib><creatorcontrib>CHO, MIN JAE</creatorcontrib><creatorcontrib>LEE, JUN HEE</creatorcontrib><creatorcontrib>LEE, HYUNG GEUN</creatorcontrib><creatorcontrib>CHUNG, KYUNG HA</creatorcontrib><creatorcontrib>KIM, IN WOO</creatorcontrib><creatorcontrib>NA, YUN SOO</creatorcontrib><creatorcontrib>YOON, YUN SOO</creatorcontrib><creatorcontrib>KIM, HA YOUNG</creatorcontrib><creatorcontrib>KIM, HYO SHIN</creatorcontrib><creatorcontrib>KIM, JI DUCK</creatorcontrib><title>SODIUM CHANNEL BLOCKERS, PREPARATION METHOD THEREOF AND USE THEREOF</title><description>The present invention relates to a compound having a blocking effect against sodium ion channels, particularly Nav1.7, a preparation method thereof and the use thereof. 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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | SODIUM CHANNEL BLOCKERS, PREPARATION METHOD THEREOF AND USE THEREOF |
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