PARTIALLY CROSS-LINKED ESTERIFIED CELLULOSE ETHERS

A partially cross-linked esterified cellulose ether having A) groups of the formula -C(O)-R-COOA or a combination of aliphatic monovalent acyl groups and groups of the formula -C(O)-R-COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, and B) having a...

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Hauptverfasser: LI, Yongfu, SPREHE, Matthias, BRACKHAGEN, Meinolf, PETERMANN, Oliver, GRASMAN, Nicholas, S, MEUNIER, David, M
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creator LI, Yongfu
SPREHE, Matthias
BRACKHAGEN, Meinolf
PETERMANN, Oliver
GRASMAN, Nicholas, S
MEUNIER, David, M
description A partially cross-linked esterified cellulose ether having A) groups of the formula -C(O)-R-COOA or a combination of aliphatic monovalent acyl groups and groups of the formula -C(O)-R-COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, and B) having a molecular weight distribution such that [Wf(>100 k)−Wf(>100 k)XL]/Wf(>100 k)XL is at least 0.20, wherein Wf(>100 k) is the total weight fraction of the esterified cellulose ether that exceeds 100,000 g/mol, and Wf(>100 k)XL is the weight fraction that exceeds 100,000 g/mol of the methylated esterified cellulose ether is useful as enteric polymer for pharmaceutical dosage forms.
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subjects CHEMISTRY
COMPOSITIONS BASED THEREON
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
POLYSACCHARIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
THEIR PREPARATION OR CHEMICAL WORKING-UP
title PARTIALLY CROSS-LINKED ESTERIFIED CELLULOSE ETHERS
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