ANTIBACTERIAL PHARMACEUTICAL COMPOSITION

The invention relates to the field of veterinary science and medicine and can be used for the prophylaxis and treatment of bacterial infections. The aim of the present invention is to design a preparation based on azithromycin in the form of a solution, having a wide spectrum of antimicrobial activi...

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Hauptverfasser: ANISKOV, ALEKSANDR ANDREEVICH, PRISTENSKIY, DMITRIY VLADIMIROVICH, SEMENOV, SERGEY VYACHESLAVOVICH, VIOLIN, BORIS VIKTOROVICH
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creator ANISKOV, ALEKSANDR ANDREEVICH
PRISTENSKIY, DMITRIY VLADIMIROVICH
SEMENOV, SERGEY VYACHESLAVOVICH
VIOLIN, BORIS VIKTOROVICH
description The invention relates to the field of veterinary science and medicine and can be used for the prophylaxis and treatment of bacterial infections. The aim of the present invention is to design a preparation based on azithromycin in the form of a solution, having a wide spectrum of antimicrobial activity, and in the form of an injection solution ready for use not only for introduction intravenously, but also for intramuscular, subcutaneous, intrauterine and intracisternal introduction. The antibacterial pharmaceutical composition comprises azithromycin, solvents and/or cosolvents, a preservative, and an antioxidant. The antioxidant is in the form of ascorbic acid or sodium ascorbate or calcium ascorbate or palmityl ascorbate or 4-methyl-2,6-di-tert-butylphenol or tert-butylhydroquinone, 2,4,5-trihydroxy-butyrophenone or sodium metabisulfite or alpha-tocopherol or thioglycerin or combinations thereof, whereas the preservative is in the form of benzyl alcohol, parabens, chlorethone, or combinations thereof with the following ratios of components by percentage mass: 5-50% azithromycin, 0.1-0.2% antioxidant, 1-2% preservative, the remainder being solvents.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title ANTIBACTERIAL PHARMACEUTICAL COMPOSITION
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