4-ALKANOYLAMINO-3-PYRAZOLONE DERIVATIVE

The present invention provides a compound which enhances the production of erythropoietin. The present invention provides, for example, a compound represented by the formula (1) wherein R 1 : -Q 1 , -Q 1 -X-Q 2 , or -Q 1 -X-Q 2 -Y-Q 3 ; Q 1 : a monocyclic or bicyclic aromatic heterocyclic group; Q 2...

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Hauptverfasser: FUKUDA, TAKESHI, SAKAMOTO, ATSUNOBU, TANAKA, NAOKI
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creator FUKUDA, TAKESHI
SAKAMOTO, ATSUNOBU
TANAKA, NAOKI
description The present invention provides a compound which enhances the production of erythropoietin. The present invention provides, for example, a compound represented by the formula (1) wherein R 1 : -Q 1 , -Q 1 -X-Q 2 , or -Q 1 -X-Q 2 -Y-Q 3 ; Q 1 : a monocyclic or bicyclic aromatic heterocyclic group; Q 2 , Q 3 : an aromatic hydrocarbon ring group or a monocyclic aromatic heterocyclic group; X: -CONH-, -CONHCH 2 -, -CH 2 OCH 2 -, -NHCH 2 CH 2 -, or the like; Y: a single bond, -O-, - (CH 2 ) n -, or -O-(-CH 2 ) n -; m, n: an integer from 1 to 3; R 2 : H or an alkyl group; and R 3 : H, an alkoxycarbonyl group, a carboxy group, an aromatic hydrocarbon ring group, or a monocyclic aromatic heterocyclic group.
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The present invention provides, for example, a compound represented by the formula (1) wherein R 1 : -Q 1 , -Q 1 -X-Q 2 , or -Q 1 -X-Q 2 -Y-Q 3 ; Q 1 : a monocyclic or bicyclic aromatic heterocyclic group; Q 2 , Q 3 : an aromatic hydrocarbon ring group or a monocyclic aromatic heterocyclic group; X: -CONH-, -CONHCH 2 -, -CH 2 OCH 2 -, -NHCH 2 CH 2 -, or the like; Y: a single bond, -O-, - (CH 2 ) n -, or -O-(-CH 2 ) n -; m, n: an integer from 1 to 3; R 2 : H or an alkyl group; and R 3 : H, an alkoxycarbonyl group, a carboxy group, an aromatic hydrocarbon ring group, or a monocyclic aromatic heterocyclic group.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20150930&amp;DB=EPODOC&amp;CC=EP&amp;NR=2832733A4$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20150930&amp;DB=EPODOC&amp;CC=EP&amp;NR=2832733A4$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FUKUDA, TAKESHI</creatorcontrib><creatorcontrib>SAKAMOTO, ATSUNOBU</creatorcontrib><creatorcontrib>TANAKA, NAOKI</creatorcontrib><title>4-ALKANOYLAMINO-3-PYRAZOLONE DERIVATIVE</title><description>The present invention provides a compound which enhances the production of erythropoietin. 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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title 4-ALKANOYLAMINO-3-PYRAZOLONE DERIVATIVE
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