EXPRESSION VECTOR ORGANIZATION, NOVEL PRODUCTION CELL GENERATION METHODS AND THEIR USE FOR THE RECOMBINANT PRODUCTION OF POLYPEPTIDES
Herein is reported an expression vector comprising- an antibody light chain expression cassette,- an antibody heavy chain expression cassette, and- a selection marker expression cassette,wherein the expression cassettes are arranged unidirectional, and wherein the expression cassettes are arranged i...
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| creator | KNOETGEN, Hendrik HUELSMANN, Peter Michael |
| description | Herein is reported an expression vector comprising- an antibody light chain expression cassette,- an antibody heavy chain expression cassette, and- a selection marker expression cassette,wherein the expression cassettes are arranged unidirectional, and wherein the expression cassettes are arranged in the 5' to 3' sequence of antibody heavy chain expression cassette, antibody light chain expression cassette and selection marker expression cassette.Further are reported herein methods for the generation of antibody producing cells and the use of these cells for the recombinant production of antibodies. |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | EXPRESSION VECTOR ORGANIZATION, NOVEL PRODUCTION CELL GENERATION METHODS AND THEIR USE FOR THE RECOMBINANT PRODUCTION OF POLYPEPTIDES |
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