CYANOMETHYLPYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS
The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.
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| creator | CHRISTOPHER, Matthew CHILDERS, Matthew Lloyd YOUNG, Jonathan, R JUNG, Joon ZHANG, Hongjun PETERSON, Scott CLOSE, Joshua, T SILIPHAIVANH, Phieng BRUBAKER, Jason KATZ, Jason David WOO, Hyun Chong SMITH, Graham Frank TORRES, Luis, E SIU, Tony |
| description | The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer. |
| format | Patent |
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CHILDERS, Matthew Lloyd ; YOUNG, Jonathan, R ; JUNG, Joon ; ZHANG, Hongjun ; PETERSON, Scott ; CLOSE, Joshua, T ; SILIPHAIVANH, Phieng ; BRUBAKER, Jason ; KATZ, Jason David ; WOO, Hyun Chong ; SMITH, Graham Frank ; TORRES, Luis, E ; SIU, Tony</creatorcontrib><description>The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180411&DB=EPODOC&CC=EP&NR=2758051B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180411&DB=EPODOC&CC=EP&NR=2758051B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHRISTOPHER, Matthew</creatorcontrib><creatorcontrib>CHILDERS, Matthew Lloyd</creatorcontrib><creatorcontrib>YOUNG, Jonathan, R</creatorcontrib><creatorcontrib>JUNG, Joon</creatorcontrib><creatorcontrib>ZHANG, Hongjun</creatorcontrib><creatorcontrib>PETERSON, Scott</creatorcontrib><creatorcontrib>CLOSE, Joshua, T</creatorcontrib><creatorcontrib>SILIPHAIVANH, Phieng</creatorcontrib><creatorcontrib>BRUBAKER, Jason</creatorcontrib><creatorcontrib>KATZ, Jason David</creatorcontrib><creatorcontrib>WOO, Hyun Chong</creatorcontrib><creatorcontrib>SMITH, Graham Frank</creatorcontrib><creatorcontrib>TORRES, Luis, E</creatorcontrib><creatorcontrib>SIU, Tony</creatorcontrib><title>CYANOMETHYLPYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS</title><description>The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLB2jnT08_d1DfGI9AmIDHKM8vdxVXB2DHLyj3D09XRxDVZwDFbwcvQLDVbw9vRzDHZV8PTz8HTyDPEPCuZhYE1LzClO5YXS3AwKbq4hzh66qQX58anFBYnJqXmpJfGuAUbmphYGpoZOhsZEKAEAzLMpZA</recordid><startdate>20180411</startdate><enddate>20180411</enddate><creator>CHRISTOPHER, Matthew</creator><creator>CHILDERS, Matthew Lloyd</creator><creator>YOUNG, Jonathan, R</creator><creator>JUNG, Joon</creator><creator>ZHANG, Hongjun</creator><creator>PETERSON, Scott</creator><creator>CLOSE, Joshua, T</creator><creator>SILIPHAIVANH, Phieng</creator><creator>BRUBAKER, Jason</creator><creator>KATZ, Jason David</creator><creator>WOO, Hyun Chong</creator><creator>SMITH, Graham Frank</creator><creator>TORRES, Luis, E</creator><creator>SIU, Tony</creator><scope>EVB</scope></search><sort><creationdate>20180411</creationdate><title>CYANOMETHYLPYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS</title><author>CHRISTOPHER, Matthew ; 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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | CYANOMETHYLPYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS |
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