CYANOMETHYLPYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS

The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

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Bibliographische Detailangaben
Hauptverfasser: CHRISTOPHER, Matthew, CHILDERS, Matthew Lloyd, YOUNG, Jonathan, R, JUNG, Joon, ZHANG, Hongjun, PETERSON, Scott, CLOSE, Joshua, T, SILIPHAIVANH, Phieng, BRUBAKER, Jason, KATZ, Jason David, WOO, Hyun Chong, SMITH, Graham Frank, TORRES, Luis, E, SIU, Tony
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.