CONDENSED PYRIMIDINE NUCLEOSIDE ANALOGS AS ANTI-VIRAL AGENTS

3-(2',3'-dideoxy-ribo-beta-L-furanosyl)[2,3-d]pyrimidin-2(3H)-one derivatives comprising 6-substitutents on the base moiety are shown to have anti-viral properties, particularly with respect to vaccinia and measles. The compounds have unnatural L ribose stereochemistry.

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Bibliographische Detailangaben
Hauptverfasser:	MCGUIGAN, CHRISTOPHER, BUGERT, JOACHIM JAKOB, FARLEIGH, LAURA ELIZABETH, PATHIRANA, RANJITH, JONES, ARWYN TOMOS
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SUGARS
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Beschreibung
Zusammenfassung:	3-(2',3'-dideoxy-ribo-beta-L-furanosyl)[2,3-d]pyrimidin-2(3H)-one derivatives comprising 6-substitutents on the base moiety are shown to have anti-viral properties, particularly with respect to vaccinia and measles. The compounds have unnatural L ribose stereochemistry.