MODIFIED ANTIBIOTIC PEPTIDES HAVING VARIABLE SYSTEMIC RELEASE

The invention relates to modified antibiotic peptides, in particular derivatives of apidaecin and oncocin, preferably having increased stability, reduced immunoreaction, and improved pharmacokinetics. In the invention, the peptide antibiotics are reversibly protected by means of a linker having the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BERTHOLD, NICOLE, NOLLMANN, FRIEDERIKE, HOFFMANN, RALF
Format: Patent
Sprache:eng ; fre ; ger
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