METHODS FOR SYNTHESIZING MOLYBDOPTERIN PRECURSOR Z DERIVATIVES

Provided herein are synthetic methods for preparing a compound of formula (I): Also provided herein are synthetic methods for preparing a compound of formula (XIII): The disclosure also provides useful intermediates, derivatives, prodrugs, and pharmaceutically acceptable salts, solvates and hydrates...

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Hauptverfasser: DAI, DANMEI, BRUNNER, ANDREAS, DIXON, RACHEL, ANNE, BAARS, SYLVIA, MYRNA, LITTLE, GILLIAN, MARY, LONG, XIANGTIAN, PROISY, NICOLAS, GEORGES, RENE, CLINCH, KEITH, WATT, DEREK, KEVIN, LANDREAU, CYRILLE, ABEL, SÉBASTIEN
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creator DAI, DANMEI
BRUNNER, ANDREAS
DIXON, RACHEL, ANNE
BAARS, SYLVIA, MYRNA
LITTLE, GILLIAN, MARY
LONG, XIANGTIAN
PROISY, NICOLAS, GEORGES, RENE
CLINCH, KEITH
WATT, DEREK, KEVIN
LANDREAU, CYRILLE, ABEL, SÉBASTIEN
description Provided herein are synthetic methods for preparing a compound of formula (I): Also provided herein are synthetic methods for preparing a compound of formula (XIII): The disclosure also provides useful intermediates, derivatives, prodrugs, and pharmaceutically acceptable salts, solvates and hydrates of the formula (I) and formula (XIII) compounds. These compounds are useful for treating diseases associated with molybdenum cofactor deficiency.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title METHODS FOR SYNTHESIZING MOLYBDOPTERIN PRECURSOR Z DERIVATIVES
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