COMPOUNDS WITH SUPER-ASPIRIN EFFECTS
A compound having the structural formula (I) and pharmaceutically acceptable salt and/or hydrates thereof, (I) wherein Y is an arylester or an C1-C8 alkylaryl ester, selected from the group consisting of: benzene, toluene, xylene, benzoic acid, benzoate, nicotinate, isonicotinate and halobenzene, wh...
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| creator | O'FLYNN, Pat RADOMSKI, Marek HARMON, Shona LEDWIDGE, Mark GILMER, John Francis MARTIN, Carlos Medina |
| description | A compound having the structural formula (I) and pharmaceutically acceptable salt and/or hydrates thereof, (I) wherein Y is an arylester or an C1-C8 alkylaryl ester, selected from the group consisting of: benzene, toluene, xylene, benzoic acid, benzoate, nicotinate, isonicotinate and halobenzene, which can be unsubstituted or substituted with at least one nitric oxide releasing group; and/or at least one of hydroxide, -Cl, -Br, a C1-C8 alkyl, benzyl, a C1-C8 alkoxy, benzyloxy, -NHC(O)R, -NH2, -NO2, -ONO2, -(CH2)nONO2, -OC(O)[(CH2)m], cyclic ONO2, -OCOArONO2, -OCOAr(CH2)nONO2 or a C1-C5 haloalkyl ester, wherein R is a C1-C8 alkyl or a C1-C8 alkoxy group, n=1-8 and m=3-10, to produce a super-aspirin effect. |
| format | Patent |
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and/or at least one of hydroxide, -Cl, -Br, a C1-C8 alkyl, benzyl, a C1-C8 alkoxy, benzyloxy, -NHC(O)R, -NH2, -NO2, -ONO2, -(CH2)nONO2, -OC(O)[(CH2)m], cyclic ONO2, -OCOArONO2, -OCOAr(CH2)nONO2 or a C1-C5 haloalkyl ester, wherein R is a C1-C8 alkyl or a C1-C8 alkoxy group, n=1-8 and m=3-10, to produce a super-aspirin effect.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190724&DB=EPODOC&CC=EP&NR=2665730B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190724&DB=EPODOC&CC=EP&NR=2665730B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>O'FLYNN, Pat</creatorcontrib><creatorcontrib>RADOMSKI, Marek</creatorcontrib><creatorcontrib>HARMON, Shona</creatorcontrib><creatorcontrib>LEDWIDGE, Mark</creatorcontrib><creatorcontrib>GILMER, John Francis</creatorcontrib><creatorcontrib>MARTIN, Carlos Medina</creatorcontrib><title>COMPOUNDS WITH SUPER-ASPIRIN EFFECTS</title><description>A compound having the structural formula (I) and pharmaceutically acceptable salt and/or hydrates thereof, (I) wherein Y is an arylester or an C1-C8 alkylaryl ester, selected from the group consisting of: benzene, toluene, xylene, benzoic acid, benzoate, nicotinate, isonicotinate and halobenzene, which can be unsubstituted or substituted with at least one nitric oxide releasing group; 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RADOMSKI, Marek ; HARMON, Shona ; LEDWIDGE, Mark ; GILMER, John Francis ; MARTIN, Carlos Medina</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP2665730B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2019</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>O'FLYNN, Pat</creatorcontrib><creatorcontrib>RADOMSKI, Marek</creatorcontrib><creatorcontrib>HARMON, Shona</creatorcontrib><creatorcontrib>LEDWIDGE, Mark</creatorcontrib><creatorcontrib>GILMER, John Francis</creatorcontrib><creatorcontrib>MARTIN, Carlos Medina</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>O'FLYNN, Pat</au><au>RADOMSKI, Marek</au><au>HARMON, Shona</au><au>LEDWIDGE, Mark</au><au>GILMER, John Francis</au><au>MARTIN, Carlos Medina</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>COMPOUNDS WITH SUPER-ASPIRIN EFFECTS</title><date>2019-07-24</date><risdate>2019</risdate><abstract>A compound having the structural formula (I) and pharmaceutically acceptable salt and/or hydrates thereof, (I) wherein Y is an arylester or an C1-C8 alkylaryl ester, selected from the group consisting of: benzene, toluene, xylene, benzoic acid, benzoate, nicotinate, isonicotinate and halobenzene, which can be unsubstituted or substituted with at least one nitric oxide releasing group; and/or at least one of hydroxide, -Cl, -Br, a C1-C8 alkyl, benzyl, a C1-C8 alkoxy, benzyloxy, -NHC(O)R, -NH2, -NO2, -ONO2, -(CH2)nONO2, -OC(O)[(CH2)m], cyclic ONO2, -OCOArONO2, -OCOAr(CH2)nONO2 or a C1-C5 haloalkyl ester, wherein R is a C1-C8 alkyl or a C1-C8 alkoxy group, n=1-8 and m=3-10, to produce a super-aspirin effect.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | COMPOUNDS WITH SUPER-ASPIRIN EFFECTS |
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