DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME

Disclosed herein are methods of inhibiting a deubiquitinase (DUB), methods of treating pathogenic infections (e.g., viral, bacterial, and/or parasitic), methods of inhibiting cell proliferation, methods of treating a neurodegenerative disease, methods of treating one or more symptoms of a neurodegen...

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Hauptverfasser: TALPAZ, MOSHE, SHOWALTER, H. D. HOLLIS, O'RIORDAN, MARY, XUAN DZIEM, DONATO, NICHOLAS, J, PERRY, JEFFREY, WILLIAM, WOBUS, CHRISTIANE, SORENSON, RODERICK, JOSEPH, JIN, YAFEI
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creator TALPAZ, MOSHE
SHOWALTER, H. D. HOLLIS
O'RIORDAN, MARY, XUAN DZIEM
DONATO, NICHOLAS, J
PERRY, JEFFREY, WILLIAM
WOBUS, CHRISTIANE
SORENSON, RODERICK, JOSEPH
JIN, YAFEI
description Disclosed herein are methods of inhibiting a deubiquitinase (DUB), methods of treating pathogenic infections (e.g., viral, bacterial, and/or parasitic), methods of inhibiting cell proliferation, methods of treating a neurodegenerative disease, methods of treating one or more symptoms of a neurodegenerative disease or a genetic disorder, and compounds, wherein the compound can have a structure of formula (III):
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME
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