A CPG-free gene for a new secreted reporter protein

The invention relates to a synthetic gene devoid of CpG nucleotide derived by genetic engineering from copepod luciferases genes that code for a new secreted luciferase with a strong bioluminescent signal. This gene display advantageous properties to be used as a reporter genes in cell based assays.

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Bibliographische Detailangaben
Hauptverfasser: REYNES, JEAN-PAUL, CASTERAN, CÉLINE, TIRABY, GÉRARD, DROCOURT, DANIEL
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The invention relates to a synthetic gene devoid of CpG nucleotide derived by genetic engineering from copepod luciferases genes that code for a new secreted luciferase with a strong bioluminescent signal. This gene display advantageous properties to be used as a reporter genes in cell based assays.