DESIGNER OSTEOGENIC PROTEINS

The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. Th...

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Hauptverfasser: SEEHERMAN, Howard Joel, JUO, Zong Sean, CAIN, Michael John, CALABRO, Valerie Perrine, BERASI, Stephen Peter, WOZNEY, John Martin, MARTINEZ, Robert Vincent Paul, BROWN, Christopher Todd
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creator SEEHERMAN, Howard Joel
JUO, Zong Sean
CAIN, Michael John
CALABRO, Valerie Perrine
BERASI, Stephen Peter
WOZNEY, John Martin
MARTINEZ, Robert Vincent Paul
BROWN, Christopher Todd
description The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title DESIGNER OSTEOGENIC PROTEINS
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