FUSED IMIDAZOLE DERIVATIVE
Provided is a novel compound which shows an antagonistic effect against T-type calcium channels, and is useful as a pharmaceutical product. A compound represented by general formula (I), and a pharmaceutical agent containing the same, are disclosed: wherein n represents the number of nitrogen atoms...
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| creator | TAKAYANAGI, KOICHI UCHINO, YUJIRO MASAKI, HIDEKAZU TAKASUGI, HIROSHI SHIMONO, RYUTARO NAGAYAMA, TOMOYUKI |
| description | Provided is a novel compound which shows an antagonistic effect against T-type calcium channels, and is useful as a pharmaceutical product. A compound represented by general formula (I), and a pharmaceutical agent containing the same, are disclosed:
wherein n represents the number of nitrogen atoms contained in the
6-membered fused aromatic ring, and is 0, 1 or 2; p represents the number of nitrogen atoms contained in the 6-membered aromatic ring, and is 0 or 1; X represents an oxygen atom, -SO 2 - or -N(R 9 )-; and R 1 to R 5 each represents a hydrogen atom or other substituents. |
| format | Patent |
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wherein n represents the number of nitrogen atoms contained in the
6-membered fused aromatic ring, and is 0, 1 or 2; p represents the number of nitrogen atoms contained in the 6-membered aromatic ring, and is 0 or 1; X represents an oxygen atom, -SO 2 - or -N(R 9 )-; and R 1 to R 5 each represents a hydrogen atom or other substituents.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2013</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130410&DB=EPODOC&CC=EP&NR=2578573A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130410&DB=EPODOC&CC=EP&NR=2578573A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TAKAYANAGI, KOICHI</creatorcontrib><creatorcontrib>UCHINO, YUJIRO</creatorcontrib><creatorcontrib>MASAKI, HIDEKAZU</creatorcontrib><creatorcontrib>TAKASUGI, HIROSHI</creatorcontrib><creatorcontrib>SHIMONO, RYUTARO</creatorcontrib><creatorcontrib>NAGAYAMA, TOMOYUKI</creatorcontrib><title>FUSED IMIDAZOLE DERIVATIVE</title><description>Provided is a novel compound which shows an antagonistic effect against T-type calcium channels, and is useful as a pharmaceutical product. A compound represented by general formula (I), and a pharmaceutical agent containing the same, are disclosed:
wherein n represents the number of nitrogen atoms contained in the
6-membered fused aromatic ring, and is 0, 1 or 2; p represents the number of nitrogen atoms contained in the 6-membered aromatic ring, and is 0 or 1; X represents an oxygen atom, -SO 2 - or -N(R 9 )-; and R 1 to R 5 each represents a hydrogen atom or other substituents.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2013</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJByCw12dVHw9PV0cYzy93FVcHEN8gxzDPEMc-VhYE1LzClO5YXS3AwKbq4hzh66qQX58anFBYnJqXmpJfGuAUam5ham5saOhsZEKAEA-rUf-w</recordid><startdate>20130410</startdate><enddate>20130410</enddate><creator>TAKAYANAGI, KOICHI</creator><creator>UCHINO, YUJIRO</creator><creator>MASAKI, HIDEKAZU</creator><creator>TAKASUGI, HIROSHI</creator><creator>SHIMONO, RYUTARO</creator><creator>NAGAYAMA, TOMOYUKI</creator><scope>EVB</scope></search><sort><creationdate>20130410</creationdate><title>FUSED IMIDAZOLE DERIVATIVE</title><author>TAKAYANAGI, KOICHI ; UCHINO, YUJIRO ; MASAKI, HIDEKAZU ; TAKASUGI, HIROSHI ; SHIMONO, RYUTARO ; NAGAYAMA, TOMOYUKI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP2578573A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2013</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>TAKAYANAGI, KOICHI</creatorcontrib><creatorcontrib>UCHINO, YUJIRO</creatorcontrib><creatorcontrib>MASAKI, HIDEKAZU</creatorcontrib><creatorcontrib>TAKASUGI, HIROSHI</creatorcontrib><creatorcontrib>SHIMONO, RYUTARO</creatorcontrib><creatorcontrib>NAGAYAMA, TOMOYUKI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TAKAYANAGI, KOICHI</au><au>UCHINO, YUJIRO</au><au>MASAKI, HIDEKAZU</au><au>TAKASUGI, HIROSHI</au><au>SHIMONO, RYUTARO</au><au>NAGAYAMA, TOMOYUKI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>FUSED IMIDAZOLE DERIVATIVE</title><date>2013-04-10</date><risdate>2013</risdate><abstract>Provided is a novel compound which shows an antagonistic effect against T-type calcium channels, and is useful as a pharmaceutical product. A compound represented by general formula (I), and a pharmaceutical agent containing the same, are disclosed:
wherein n represents the number of nitrogen atoms contained in the
6-membered fused aromatic ring, and is 0, 1 or 2; p represents the number of nitrogen atoms contained in the 6-membered aromatic ring, and is 0 or 1; X represents an oxygen atom, -SO 2 - or -N(R 9 )-; and R 1 to R 5 each represents a hydrogen atom or other substituents.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | FUSED IMIDAZOLE DERIVATIVE |
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