Novel lipid peptide and hydrogel
There is provided a lipid peptide that is capable of forming a hydrogel with an extremely small amount thereof over a liquid property range from acidic to alkaline, and a hydrogel having high environmental suitability, biocompatibility and biodegradability. A lipid peptide represented by Formula (1)...
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| creator | MARUYAMA, TATSUO GOTOH, MASAHIRO MIYAJI, NOBUHIDE IWAMA, TAKEHISA KOHDA, DAISUKE |
| description | There is provided a lipid peptide that is capable of forming a hydrogel with an extremely small amount thereof over a liquid property range from acidic to alkaline, and a hydrogel having high environmental suitability, biocompatibility and biodegradability. A lipid peptide represented by Formula (1):
(where R 1 represents an aliphatic group having 9 to 23 carbon atoms;
R 2 , R 3 , R 4 and R 5 independently represent a hydrogen atom, an alkyl group having 1 to 7 carbon atom(s) which optionally has a branched chain having 1 to 3 carbon atom(s), a phenylmethyl group, a phenylethyl group or a -(CH 2 ) n -X group, and at least one of R 2 , R 3 , R 4 and R 5 represents a -(CH 2 ) n -X group;
n represents the number of 1 to 4; X represents an amino group, a guanidino group, a -CONH 2 group or a 5-membered ring, a 6-membered ring or a fused heterocyclic ring composed of a 5-membered ring and a 6-membered ring which optionally have 1 to 3 nitrogen atom(s); and m represents 1 or 2), and a hydrogel comprising the lipid peptide. |
| format | Patent |
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(where R 1 represents an aliphatic group having 9 to 23 carbon atoms;
R 2 , R 3 , R 4 and R 5 independently represent a hydrogen atom, an alkyl group having 1 to 7 carbon atom(s) which optionally has a branched chain having 1 to 3 carbon atom(s), a phenylmethyl group, a phenylethyl group or a -(CH 2 ) n -X group, and at least one of R 2 , R 3 , R 4 and R 5 represents a -(CH 2 ) n -X group;
n represents the number of 1 to 4; X represents an amino group, a guanidino group, a -CONH 2 group or a 5-membered ring, a 6-membered ring or a fused heterocyclic ring composed of a 5-membered ring and a 6-membered ring which optionally have 1 to 3 nitrogen atom(s); and m represents 1 or 2), and a hydrogel comprising the lipid peptide.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES</subject><creationdate>2014</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140326&DB=EPODOC&CC=EP&NR=2559697B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140326&DB=EPODOC&CC=EP&NR=2559697B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MARUYAMA, TATSUO</creatorcontrib><creatorcontrib>GOTOH, MASAHIRO</creatorcontrib><creatorcontrib>MIYAJI, NOBUHIDE</creatorcontrib><creatorcontrib>IWAMA, TAKEHISA</creatorcontrib><creatorcontrib>KOHDA, DAISUKE</creatorcontrib><title>Novel lipid peptide and hydrogel</title><description>There is provided a lipid peptide that is capable of forming a hydrogel with an extremely small amount thereof over a liquid property range from acidic to alkaline, and a hydrogel having high environmental suitability, biocompatibility and biodegradability. A lipid peptide represented by Formula (1):
(where R 1 represents an aliphatic group having 9 to 23 carbon atoms;
R 2 , R 3 , R 4 and R 5 independently represent a hydrogen atom, an alkyl group having 1 to 7 carbon atom(s) which optionally has a branched chain having 1 to 3 carbon atom(s), a phenylmethyl group, a phenylethyl group or a -(CH 2 ) n -X group, and at least one of R 2 , R 3 , R 4 and R 5 represents a -(CH 2 ) n -X group;
n represents the number of 1 to 4; X represents an amino group, a guanidino group, a -CONH 2 group or a 5-membered ring, a 6-membered ring or a fused heterocyclic ring composed of a 5-membered ring and a 6-membered ring which optionally have 1 to 3 nitrogen atom(s); and m represents 1 or 2), and a hydrogel comprising the lipid peptide.</description><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2014</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFDwyy9LzVHIySzITFEoSC0oyUxJVUjMS1HIqEwpyk9PzeFhYE1LzClO5YXS3AwKbq4hzh66qQX58anFBYnJqXmpJfGuAUamppZmluZOhsZEKAEA_2Uk2Q</recordid><startdate>20140326</startdate><enddate>20140326</enddate><creator>MARUYAMA, TATSUO</creator><creator>GOTOH, MASAHIRO</creator><creator>MIYAJI, NOBUHIDE</creator><creator>IWAMA, TAKEHISA</creator><creator>KOHDA, DAISUKE</creator><scope>EVB</scope></search><sort><creationdate>20140326</creationdate><title>Novel lipid peptide and hydrogel</title><author>MARUYAMA, TATSUO ; GOTOH, MASAHIRO ; MIYAJI, NOBUHIDE ; IWAMA, TAKEHISA ; KOHDA, DAISUKE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP2559697B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2014</creationdate><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><toplevel>online_resources</toplevel><creatorcontrib>MARUYAMA, TATSUO</creatorcontrib><creatorcontrib>GOTOH, MASAHIRO</creatorcontrib><creatorcontrib>MIYAJI, NOBUHIDE</creatorcontrib><creatorcontrib>IWAMA, TAKEHISA</creatorcontrib><creatorcontrib>KOHDA, DAISUKE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MARUYAMA, TATSUO</au><au>GOTOH, MASAHIRO</au><au>MIYAJI, NOBUHIDE</au><au>IWAMA, TAKEHISA</au><au>KOHDA, DAISUKE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Novel lipid peptide and hydrogel</title><date>2014-03-26</date><risdate>2014</risdate><abstract>There is provided a lipid peptide that is capable of forming a hydrogel with an extremely small amount thereof over a liquid property range from acidic to alkaline, and a hydrogel having high environmental suitability, biocompatibility and biodegradability. A lipid peptide represented by Formula (1):
(where R 1 represents an aliphatic group having 9 to 23 carbon atoms;
R 2 , R 3 , R 4 and R 5 independently represent a hydrogen atom, an alkyl group having 1 to 7 carbon atom(s) which optionally has a branched chain having 1 to 3 carbon atom(s), a phenylmethyl group, a phenylethyl group or a -(CH 2 ) n -X group, and at least one of R 2 , R 3 , R 4 and R 5 represents a -(CH 2 ) n -X group;
n represents the number of 1 to 4; X represents an amino group, a guanidino group, a -CONH 2 group or a 5-membered ring, a 6-membered ring or a fused heterocyclic ring composed of a 5-membered ring and a 6-membered ring which optionally have 1 to 3 nitrogen atom(s); and m represents 1 or 2), and a hydrogel comprising the lipid peptide.</abstract><oa>free_for_read</oa></addata></record> |
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| language | eng ; fre ; ger |
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| subjects | CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES |
| title | Novel lipid peptide and hydrogel |
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