Polymorphic and amorphous salt forms of squalamine dilactate

The invention relates to select squalamine salts, methods of their synthesis, their therapeutic use and their advantages relating to manufacturing, product stability and toxicity. More specifically, this application is directed to various forms of the dilactate salt of squalamine and their utility i...

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Hauptverfasser: GILBERT, CHARLES, CHELLQUIST, ERIC, DOUBLEDAY, MARY, ZHANG, XUEHAI, AMBRUSTER, KYLE, MCLANE, MICHAEL, LEVITT, ROY
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creator GILBERT, CHARLES
CHELLQUIST, ERIC
DOUBLEDAY, MARY
ZHANG, XUEHAI
AMBRUSTER, KYLE
MCLANE, MICHAEL
LEVITT, ROY
description The invention relates to select squalamine salts, methods of their synthesis, their therapeutic use and their advantages relating to manufacturing, product stability and toxicity. More specifically, this application is directed to various forms of the dilactate salt of squalamine and their utility in inhibiting neovascularization and endothelial cell proliferation
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STEROIDS
title Polymorphic and amorphous salt forms of squalamine dilactate
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