Intermediates for the preparation of halichondrin B

The present invention provides macrocyclic compounds, synthesis of the same intermediates thereto. Such compounds, and compositions thereof, are useful for treating or presenting proliferative disorders Formula (F-4).

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Bibliographische Detailangaben
Hauptverfasser: BENAYOUD, FARID, CALKINS, TREVOR LEE, FANG, FRANCIS G, CHASE, CHARLES E, CHRIST, WILLIAM
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention provides macrocyclic compounds, synthesis of the same intermediates thereto. Such compounds, and compositions thereof, are useful for treating or presenting proliferative disorders Formula (F-4).