METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT

Provided herein are compounds having anti-proliferative effect. Also provided are compounds that can modulate the activity of multi-domain proteins comprising a dimerization arm and interdomain tether, such as EGFR, where an untethered, extended conformation is the active state and a tethered confor...

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Hauptverfasser:	TURCHI, IGNATIUS, HERRON, JEFFREY D, MUGRAGE, BENJAMIN, WINES, PAM, SILLS, MATTHEW, ONG, JANE, LODATO, NICHOLAS J, FEAVER, WILLIAM J, ALLOCCO, JOHN, PINE, COREY
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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