PROCESS FOR THE PREPARATION OF THYROID HORMONES AND SALTS THEREOF

PROCESS FOR THE PREPARATION OF THYROID HORMONES AND SALTS THEREOF

The present invention generally refers to a process for the preparation of L-thyroxine derivatives. More in particular, the present invention relates to a iodination reaction of an aromatic derivative with an appropriate iodinating agent, so to afford the related iodinated compound as disodium salt,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CAPPELLETTI, Enrico, GAZZETTO, Sonia, VISCARDI, Carlo Felice, GALIMBERTI, Laura, SINI, Loredana
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention generally refers to a process for the preparation of L-thyroxine derivatives. More in particular, the present invention relates to a iodination reaction of an aromatic derivative with an appropriate iodinating agent, so to afford the related iodinated compound as disodium salt, which may represent a useful intermediate for the synthesis of the L-thyroxine mono-sodium salt, and the free form thereof.