REVERSE HEXAGONAL MESOPHASES (H II) AND USES THEREOF

REVERSE HEXAGONAL MESOPHASES (H II) AND USES THEREOF

Reverse hexagonal mesophase (HII) liquid crystals provide multi-component hexagonal systems for use in solubilizing and/or protecting from degradation one or more bio-macromolecule and/or active material, and relates to therapeutic and non-therapeutic applications, such as an oral delivery system, w...

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Hauptverfasser: MISHRAKI, Tehila, BITANRVKOVSKY, Liron, GARTI, Nissim, ASERIN, Abraham, AMAR-YULI, Idit, LIBSTER, Dima
Format: Patent
Sprache:eng ; fre ; ger
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator MISHRAKI, Tehila
BITANRVKOVSKY, Liron
GARTI, Nissim
ASERIN, Abraham
AMAR-YULI, Idit
LIBSTER, Dima
description Reverse hexagonal mesophase (HII) liquid crystals provide multi-component hexagonal systems for use in solubilizing and/or protecting from degradation one or more bio-macromolecule and/or active material, and relates to therapeutic and non-therapeutic applications, such as an oral delivery system, where the mesophase is adapted for oral administration. The present invention provides the formation of mesophase systems of ternary glycerol monooleate (GMO)/water combinations which comprise at least one triglyceride or an equivalent thereof. At least one biomacromolecule or drug is incorporated in the mesophase of a pharmaceutical composition or oral delivery system.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title REVERSE HEXAGONAL MESOPHASES (H II) AND USES THEREOF
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