HUMANISED PSORIASIS MODEL

The invention relates to a novel humanised animal psoriasis model. Said model is generated by means of the grafting of humanised skin equivalents in the animal, the injection of T lymphocytes and cytokines involved in the generation of the disease in humans, and the implementation of the tape-stripp...

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Hauptverfasser: CARRETERO TRILLO, MARTA, MEANA INFIESTA, ALVARO, GARCIA DIEZ, MARTA, JORCANO NOVAL, JOSE LUIS, GUERRERO ASPIZUA, SARA, LARCHER LAGUZZI, FERNANDO, DEL RIO NECHAEVSKY, MARCELA
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creator CARRETERO TRILLO, MARTA
MEANA INFIESTA, ALVARO
GARCIA DIEZ, MARTA
JORCANO NOVAL, JOSE LUIS
GUERRERO ASPIZUA, SARA
LARCHER LAGUZZI, FERNANDO
DEL RIO NECHAEVSKY, MARCELA
description The invention relates to a novel humanised animal psoriasis model. Said model is generated by means of the grafting of humanised skin equivalents in the animal, the injection of T lymphocytes and cytokines involved in the generation of the disease in humans, and the implementation of the tape-stripping technique for damaging said grafted equivalents. Said model can be used to study the disease and to identify and evaluate the efficiency of the compounds in controlling said disease.
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Said model is generated by means of the grafting of humanised skin equivalents in the animal, the injection of T lymphocytes and cytokines involved in the generation of the disease in humans, and the implementation of the tape-stripping technique for damaging said grafted equivalents. 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subjects AGRICULTURE
ANIMAL HUSBANDRY
CARE OF BIRDS, FISHES, INSECTS
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
NEW BREEDS OF ANIMALS
PHYSICS
REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR
TESTING
TRAPPING
title HUMANISED PSORIASIS MODEL
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