LIPID NANOPARTICLES FOR GENE THERAPY
The present invention relates to a lipid nanoparticle system comprising a lipid component, a cationic surfactant, a non-ionic surfactant, a polysaccharide and, optionally, a positively charged peptide, useful for the release of pharmacologically active molecules, and especially for transfecting gene...
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| creator | SOLINIS ASPIAZU, MARIA ANGELES PEDRAZ MUNOZ, JOSE LUIS DEL POZO RODRIGUEZ, ANA RODRIGUEZ GASCON, ALICIA DELGADO SAN VICENTE, DIEGO |
| description | The present invention relates to a lipid nanoparticle system comprising a lipid component, a cationic surfactant, a non-ionic surfactant, a polysaccharide and, optionally, a positively charged peptide, useful for the release of pharmacologically active molecules, and especially for transfecting genetic material into cells and/or tissues. It also relates to methods for obtaining nanoparticles, to pharmaceutical compositions comprising it, as well as to the use thereof in gene therapy. |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | LIPID NANOPARTICLES FOR GENE THERAPY |
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