NEW GRANULATING PROCESS AND THUS PREPARED GRANULATE

NEW GRANULATING PROCESS AND THUS PREPARED GRANULATE

The present invention relates to a process for manufacturing microcrystalline ezetimibe containing granulate, wherein a) ezetimibe is dissolved; b) the dissolved ezetimibe is precipitated with water, which if necessary contains pharmaceutical excipients, preferably lauryl-sulfate derivatives, and c)...

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Hauptverfasser: UJFALUSSY, GYOERGY, AGYAGOS, MONIKA, LEVENTISZNE HUSZAR, MAGDOLNA, ZSIGMOND, ZSOLT, TOELGYESI, ZOLTAN, TONKA-NAGY, PETER
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator UJFALUSSY, GYOERGY
AGYAGOS, MONIKA
LEVENTISZNE HUSZAR, MAGDOLNA
ZSIGMOND, ZSOLT
TOELGYESI, ZOLTAN
TONKA-NAGY, PETER
description The present invention relates to a process for manufacturing microcrystalline ezetimibe containing granulate, wherein a) ezetimibe is dissolved; b) the dissolved ezetimibe is precipitated with water, which if necessary contains pharmaceutical excipients, preferably lauryl-sulfate derivatives, and c) granulates are formed from the obtained suspension by spraying the suspension onto pharmaceutical excipients. A further aspect of the present invention is the granulate obtained by the present process and the pharmaceutical composition containing such granulate.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title NEW GRANULATING PROCESS AND THUS PREPARED GRANULATE
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