DRAIN DOWN AND RE-FEED OF MICROCARRIER BIOREACTOR

Disclosed is a method of increasing product yield per culture in a population of bound product-secreting cells in a bioreactor, the method comprising: semi-harvesting product by removing a volume of the culture medium with a first-secreted product concentration; re-feeding the bound population of pr...

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Bibliographische Detailangaben
Hauptverfasser: GUERTIN, Patrick, M, CROWELL, Joseph, D
Format: Patent
Sprache:eng ; fre ; ger
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