Vaccine compositions based on modified gp41 immunogens

Vaccine compositions based on modified gp41 immunogens

The invention relates to relates to human immunodeficiency virus (HIV) immunogens based on gp41 epitopes located in the membrane proximal extracellular region (MPER). The immunogens of the present invention are capable of inducing the expression of neutralizing antibodies. Various forms of these iso...

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Hauptverfasser: CARRILLO MOLINA, JORGE, CURRIU MARTI, MARTA, BLANCO ARBUES, JULIAN MIGUEL
Format: Patent
Sprache:eng ; fre ; ger
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CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator CARRILLO MOLINA, JORGE
CURRIU MARTI, MARTA
BLANCO ARBUES, JULIAN MIGUEL
description The invention relates to relates to human immunodeficiency virus (HIV) immunogens based on gp41 epitopes located in the membrane proximal extracellular region (MPER). The immunogens of the present invention are capable of inducing the expression of neutralizing antibodies. Various forms of these isolated immunogens are disclosed and exemplified. Isolated nucleic acid molecules expressing relevant portions of these immunogens, as well as the vectors and host cells utilized for their production, are also within the scope of the present invention.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Vaccine compositions based on modified gp41 immunogens
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