COMPOUNDS
A compound of formula (I) Or its salts or pharmaceutically acceptable derivatives thereof wherein; A represents a chemical moiety with the general formula (II): X is selected from a group consisting of CH2, C( O), CH(R5), C(R5)(R6) or C(R5)(R6)CH2; R1 is selected from the group consisting of optiona...
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creator | MADGE, David HARTZOULAKIS, Basil JONES, Simon, Mark MULLA, Mushtaq HAMLYN, Richard, John JOHN, Derek, Edward |
description | A compound of formula (I) Or its salts or pharmaceutically acceptable derivatives thereof wherein; A represents a chemical moiety with the general formula (II): X is selected from a group consisting of CH2, C( O), CH(R5), C(R5)(R6) or C(R5)(R6)CH2; R1 is selected from the group consisting of optionally substituted arylalkyl, and optionally substituted heteroarylalkyl; R2 is selected from the group consisting of optionally substituted aryl or optionally substituted heteroaryl or NR7R8; R3 R4 R5 R6 R7 and R8 are as defined herein; and n=1 or 2 is provided. Pharmaceutical compositions comprising the compounds are also provided. The compounds are useful in treating various conditions including arrhythmia. |
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Pharmaceutical compositions comprising the compounds are also provided. 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Pharmaceutical compositions comprising the compounds are also provided. The compounds are useful in treating various conditions including arrhythmia.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZOB09vcN8A_1cwnmYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxrgFGJsYWBiYmTobGRCgBABO_G0Q</recordid><startdate>20190123</startdate><enddate>20190123</enddate><creator>MADGE, David</creator><creator>HARTZOULAKIS, Basil</creator><creator>JONES, Simon, Mark</creator><creator>MULLA, Mushtaq</creator><creator>HAMLYN, Richard, John</creator><creator>JOHN, Derek, Edward</creator><scope>EVB</scope></search><sort><creationdate>20190123</creationdate><title>COMPOUNDS</title><author>MADGE, David ; HARTZOULAKIS, Basil ; JONES, Simon, Mark ; MULLA, Mushtaq ; HAMLYN, Richard, John ; JOHN, Derek, Edward</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP2438044B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2019</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>MADGE, David</creatorcontrib><creatorcontrib>HARTZOULAKIS, Basil</creatorcontrib><creatorcontrib>JONES, Simon, Mark</creatorcontrib><creatorcontrib>MULLA, Mushtaq</creatorcontrib><creatorcontrib>HAMLYN, Richard, John</creatorcontrib><creatorcontrib>JOHN, Derek, Edward</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MADGE, David</au><au>HARTZOULAKIS, Basil</au><au>JONES, Simon, Mark</au><au>MULLA, Mushtaq</au><au>HAMLYN, Richard, John</au><au>JOHN, Derek, Edward</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>COMPOUNDS</title><date>2019-01-23</date><risdate>2019</risdate><abstract>A compound of formula (I) Or its salts or pharmaceutically acceptable derivatives thereof wherein; A represents a chemical moiety with the general formula (II): X is selected from a group consisting of CH2, C( O), CH(R5), C(R5)(R6) or C(R5)(R6)CH2; R1 is selected from the group consisting of optionally substituted arylalkyl, and optionally substituted heteroarylalkyl; R2 is selected from the group consisting of optionally substituted aryl or optionally substituted heteroaryl or NR7R8; R3 R4 R5 R6 R7 and R8 are as defined herein; and n=1 or 2 is provided. Pharmaceutical compositions comprising the compounds are also provided. The compounds are useful in treating various conditions including arrhythmia.</abstract><oa>free_for_read</oa></addata></record> |
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title | COMPOUNDS |
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