BIOABSORBABLE POLYMER CONTAINING 2-HYDROXYACID MONOMERS

The present invention relates to a method of producing 2-hydroxyacid-containing polymer comprising expressing in an organism genes encoding a polyhydroxyalkanoate (PHA) synthase and at least one enzyme for the production of 2-hydroxyacyl Co-A. Preferably the method is a method of producing glycolic...

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Bibliographische Detailangaben
Hauptverfasser:	Martin, David P, Skraly, Frank A
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a method of producing 2-hydroxyacid-containing polymer comprising expressing in an organism genes encoding a polyhydroxyalkanoate (PHA) synthase and at least one enzyme for the production of 2-hydroxyacyl Co-A. Preferably the method is a method of producing glycolic acid-containing polyhydroxyalkanoate polymer comprising feeding glycolic acid or a substrate converted to 2-hydroxyacid units to bacteria or plants expressing a polyhydroxyalkanoate (PHA) synthase and at least one enzyme for the production of 2-hydroxyacyl Co-A to produce the glycolic acid-containing polymer. The present invention also relates to the use of a laser to prepare a porous PHA polymer, by melt or solvent processing the PHA into a mold and perforating the material with the laser to achieve the desired porosity.