Novel crystalline form of atorvastatin hemi-calcium salt, hydrate thereof, and method of producing the same

Novel crystalline form of atorvastatin hemi-calcium salt, hydrate thereof, and method of producing the same

The present invention provides a novel crystalline form of [R-(R*,R*)]-2-(4-fluorophenyl)-²,´-dihydroxy-5-(1-mthylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-heptanoic acid hemi-calcium salt (atorvastatin hemi-calcium salt) of the following formula 1, which is known to be useful as a drug,...

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Hauptverfasser: SON, HOE, JOO, LEE, KYUNG, JU, CHANG, SUN, HO, CHOI, DOO, SEONG, OH, DO, YEON
Format: Patent
Sprache:eng ; fre ; ger
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator SON, HOE, JOO
LEE, KYUNG, JU
CHANG, SUN, HO
CHOI, DOO, SEONG
OH, DO, YEON
description The present invention provides a novel crystalline form of [R-(R*,R*)]-2-(4-fluorophenyl)-²,´-dihydroxy-5-(1-mthylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-heptanoic acid hemi-calcium salt (atorvastatin hemi-calcium salt) of the following formula 1, which is known to be useful as a drug, a hydrate thereof and a preparation method thereof:
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Novel crystalline form of atorvastatin hemi-calcium salt, hydrate thereof, and method of producing the same
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