METHOD OF SYNTHESIZING [18F]SFB USING MICROSYNTHESIS TECHNIQUE

A method for synthesizing [ 18 F]SFB is disclosed, which comprises using a microreactor including a substrate having one channel formed therein so as to have a cross-sectional width of 1 mm or less and a cross-sectional depth of 1 mm or less, the channel being connected to a raw material injection p...

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Hauptverfasser: KUGE YUJI, NAKANISHI HIROAKI, SAIKI HIDEKAZU, KAWASHIMA HIDEKAZU, KIMURA HIROYUKI, SAJI HIDEO, TOMATSU KENJI
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creator KUGE YUJI
NAKANISHI HIROAKI
SAIKI HIDEKAZU
KAWASHIMA HIDEKAZU
KIMURA HIROYUKI
SAJI HIDEO
TOMATSU KENJI
description A method for synthesizing [ 18 F]SFB is disclosed, which comprises using a microreactor including a substrate having one channel formed therein so as to have a cross-sectional width of 1 mm or less and a cross-sectional depth of 1 mm or less, the channel being connected to a raw material injection port and a first reagent injection port at one end thereof, and connected to a second reagent injection port at a position far from the one end thereof, and connected to a third reagent injection port at a position far from the second reagent injection port in a direction toward another end thereof, and connected to a liquid discharge port at the other end thereof; and continuously performing a three-step reaction by allowing a reaction solution to flow through the channel serving as a reaction channel from the one end to the other end thereof without taking out the reaction solution from anywhere between the one end and the other end of the channel.
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subjects APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title METHOD OF SYNTHESIZING [18F]SFB USING MICROSYNTHESIS TECHNIQUE
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